Incident Prescriptions of Anti‐Dementia Medications in Previously Independent Nonagenarian Sepsis Survivors

Key Points The trajectory of severe cognitive impairment following intensive care in the oldest‐old remains poorly quantified. Among previously independent nonagenarian sepsis survivors, 4.1% were newly prescribed anti‐dementia medications within 6 months post‐ICU. This initiation suggests either an accelerated dementia, the unmasking of previously undiagnosed dementia, or a “prescribing cascade.” Comprehensive post‐ICU care should include cognitive screening tailored for our oldest, most vulnerable survivors.

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Publication Details

Journal
International Journal of Geriatric Psychiatry
Published
2026-05-30
DOI
https://doi.org/10.1002/gps.70227
Primary Topic
Intensive Care Unit Cognitive Disorders
Type
article
Field-Weighted Citation Impact
0.00

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article

Incident Prescriptions of Anti‐Dementia Medications in Previously Independent Nonagenarian Sepsis Survivors

Yuichiro Shimoyama, Noriko Kadono, Osamu Umegaki
International Journal of Geriatric Psychiatry
Intensive Care Unit Cognitive Disorders
article

Incident Prescriptions of Anti‐Dementia Medications in Previously Independent Nonagenarian Sepsis Survivors

Yuichiro Shimoyama, Noriko Kadono, Osamu Umegaki
article en

Abstract

Key Points The trajectory of severe cognitive impairment following intensive care in the oldest‐old remains poorly quantified. Among previously independent nonagenarian sepsis survivors, 4.1% were newly prescribed anti‐dementia medications within 6 months post‐ICU. This initiation suggests either an accelerated dementia, the unmasking of previously undiagnosed dementia, or a “prescribing cascade.” Comprehensive post‐ICU care should include cognitive screening tailored for our oldest, most vulnerable survivors.

International Journal of Geriatric PsychiatryVol. 41(6)
Osaka University of Pharmaceutical Sciences (JP)
Japan Society for the Promotion of Science
Openalex Percentile: Top 5%
Intensive Care Unit Cognitive Disorders
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