What’s next for VI-RADS? Updates and future perspectives from the ACR VI-RADS steering committee

Since the introduction of the Vesical Imaging-Reporting and Data System (VI-RADS), MRI has become an important imaging modality in the management of patients with bladder cancer. Its excellent diagnostic performance for determining muscle invasion in bladder cancer has been supported by numerous prospective and retrospective studies. Nevertheless, there needs to be continued improvement of the diagnostic performance of VI-RADS and sustained efforts to address remaining unmet clinical needs within the field of bladder cancer. In this paper, we highlight several such areas, some of which are actively being investigated. These include (1) whether to use intravenous contrast media or not (multiparametric vs. biparametric MRI), (2) quantitative metrics to enhance assessment of muscle invasion, (3) anatomic locations that come with pitfalls in staging, (4) introduction of bladder MRI image quality, (5) neoadjuvant chemotherapy VI-RADS (nacVI-RADS) and other considerations needed in the treatment response assessment after systemic therapies, (6) need for wider adoption, training, and implementation, and (7) application of artificial intelligence.

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Publication Details

Journal
Cancer Imaging
Published
2026-05-30
DOI
https://doi.org/10.1186/s40644-026-01062-4
Primary Topic
Cardiac Valve Diseases and Treatments
Type
article
Field-Weighted Citation Impact
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article

What’s next for VI-RADS? Updates and future perspectives from the ACR VI-RADS steering committee

Hebert Alberto Vargas, Lyndon Luk, Jason Efstathiou, Valdair F. Muglia et al.
Cancer Imaging
Cardiac Valve Diseases and Treatments
article

What’s next for VI-RADS? Updates and future perspectives from the ACR VI-RADS steering committee

Hebert Alberto Vargas, Lyndon Luk, Jason Efstathiou, Valdair F. Muglia, Bernadette Redd, J. Alfred Witjes, Maarten de Rooij, Sungmin Woo, Valeria Panebianco, Samuel J. Galgano, Alberto Briganti, Mitsuru Takeuchi
article en

Abstract

Since the introduction of the Vesical Imaging-Reporting and Data System (VI-RADS), MRI has become an important imaging modality in the management of patients with bladder cancer. Its excellent diagnostic performance for determining muscle invasion in bladder cancer has been supported by numerous prospective and retrospective studies. Nevertheless, there needs to be continued improvement of the diagnostic performance of VI-RADS and sustained efforts to address remaining unmet clinical needs within the field of bladder cancer. In this paper, we highlight several such areas, some of which are actively being investigated. These include (1) whether to use intravenous contrast media or not (multiparametric vs. biparametric MRI), (2) quantitative metrics to enhance assessment of muscle invasion, (3) anatomic locations that come with pitfalls in staging, (4) introduction of bladder MRI image quality, (5) neoadjuvant chemotherapy VI-RADS (nacVI-RADS) and other considerations needed in the treatment response assessment after systemic therapies, (6) need for wider adoption, training, and implementation, and (7) application of artificial intelligence.

Cancer Imaging
Radboud University Nijmegen (NL), Vita-Salute San Raffaele University (IT), Kawasaki Medical School (JP), Columbia University Irving Medical Center (US), Radboud University Medical Center (NL), University of Alabama at Birmingham (US), NYU Langone Health (US), IRCCS Ospedale San Raffaele (IT), Center for Cancer Research (US), National Institutes of Health Clinical Center (US), Clinics Hospital of Ribeirão Preto (BR), New York University (US), Sapienza University of Rome (IT)
Openalex Percentile: Top 6%
Cardiac Valve Diseases and Treatments
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