Precision DLP Printing of Multifunctional SilMA Hydrogels Enabled by Sepia Melanin for On-Demand Wound Therapy
evaluations confirmed that the scaffold effectively controls infection (nearly 98% antibacterial rate), mitigates oxidative stress, increases the polarization of M2 macrophages, and accelerates wound closure through enhanced collagen deposition and neovascularization. This work establishes a unified strategy that seamlessly integrates high-resolution printability, intrinsic bioactivity, and on-demand responsiveness into a single biocompatible platform, offering a versatile and generalizable approach for advanced tissue regeneration in infection-compromised environments.
Authors
- Xuanwen Wang (ORCID: https://orcid.org/0000-0003-3499-3859)
- Siying Liu (ORCID: https://orcid.org/0009-0007-2084-7945)
- Xuyang Zhang (ORCID: https://orcid.org/0000-0001-5084-0225)
- Xiaoliang Cui (ORCID: https://orcid.org/0009-0007-8818-1190)
- Zhongxiu Chen
- Jun Zhang (ORCID: https://orcid.org/0000-0002-7662-0295)
- Caiyu Zhou
Institutions
- Chinese Academy of Sciences (CN)
- National Institute of Fashion Technology (IN)
- Center for Excellence in Molecular Cell Science (CN)
- Broward Health (US)
- Broward College (US)
Publication Details
- Journal
- ACS Applied Materials & Interfaces
- Published
- 2026-05-30
- DOI
- https://doi.org/10.1021/acsami.6c05305
- Primary Topic
- 3D Printing in Biomedical Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation
- Priority Academic Program Development of Jiangsu Higher Education Institutions
- Natural Science Research of Jiangsu Higher Education Institutions of China