TIF1β Promotes Myocardial Ischemia-Reperfusion Injury by Stabilizing TRAF6 through Mediating TRAF6 SUMOylation
Myocardial ischemia-reperfusion injury (MIRI) exacerbates myocardial damage, resulting in a further decline in heart function. Abnormally high TRAF6 expression was reported in MIRI. However, what actually causes the abnormally elevated expression of TRAF6 in MIRI is still unclear and needs further study.
Authors
- Xi Zhang (ORCID: https://orcid.org/0000-0002-4638-3997)
- Xinping Du (ORCID: https://orcid.org/0000-0003-2912-2397)
- Guoxing Zuo
- Chengzhi Lu
- Yue Nan
Institutions
- Tianjin First Center Hospital (CN)
- Fifth Tianjin Central Hospital (CN)
- Tianjin Medical University (CN)
Publication Details
- Journal
- International Heart Journal
- Published
- 2026-05-29
- DOI
- https://doi.org/10.1536/ihj.25-377
- Primary Topic
- NF-κB Signaling Pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.00