Intramolecular Asymmetric Iodoetherification of ortho-Allylphenols Catalyzed by Chiral Multinuclear Zn Bis(aminoimino)binaphthoxide

The catalytic, asymmetric intramolecular iodoetherification of ortho-allylphenols was achieved using a multinuclear zinc bis(aminoimino)binaphthoxide complex, generating dihydrobenzofuran compounds in up to 99% yields with 85% ee. Azidation of the chiral compound 2-iodomethyldihydrobenzofuran and a subsequent click reaction with phenylacetylene gave the corresponding triazolesubstituted dihydrobenzofuran while maintaining the original chirality.