68Ga-FAPI PET/CT features of thoracic sarcoidosis: a prospective observational study

BACKGROUND: Ga-FAPI) PET/CT in sarcoidosis, with particular emphasis on lesion uptake patterns and intensity, as well as the correlation with disease activity. METHODS: F-FDG PET/CT scans from 16 sarcoidosis patients. For both imaging groups, the maximum and mean standardized uptake values (SUVmax and SUVmean, respectively) and corrected lesion-to-background ratio (LBR) were calculated. RESULTS: F-FDG uptake parameters in the retrospective cohort. CONCLUSIONS: Ga-FAPI PET/CT can be useful for evaluating both active and chronic granulomatous inflammation. It is also potentially valuable for determining disease extent, detecting occult disease, and monitoring treatment response in sarcoidosis.