Surgical Management of Essential Blepharospasm: Long-Term Results After Orbicularis Myectomy

PURPOSE: To evaluate the long-term functional and aesthetic outcomes of orbicularis myectomy in patients with medically refractory benign essential blepharospasm and to contextualize findings within current surgical literature. METHODS: A retrospective analysis was conducted on 80 patients (129 eyelids) who underwent subtotal orbicularis myectomy between 2014 and 2023. Bilateral procedures were performed sequentially. Mean follow-up was 84 months (range: 24-144.3). Surgery was offered after failure of initial botulinum toxin injections, with a mean delay of 18.5 months. RESULTS: At 6 and 12 months postoperatively, 72% of patients experienced functional improvement, with a mean 53% reduction in spasm severity. However, only 41% maintained long-term benefit. Spasms recurred in 86%, and only 7.5% achieved complete resolution without further botulinum toxin injections. Aesthetic outcomes were favorable in 96% of cases and remained stable over time. The frequency of botulinium toxin injections decreased from 1 every 3 months to every 4 months, though this change was not statistically significant (p = 0.12). Botulinum toxin dose was significantly reduced at 12 months (p < 0.001), but not at final follow-up (p = 0.2872), suggesting a temporary postoperative benefit. No major complications were observed. Transient lagophthalmos occurred in 3% of cases; 1 case required surgical revision. There was no significant association between long-term disabling symptoms and age (p = 0.61), gender (p = 0.12), or active smoking (p = 0.49). CONCLUSION: Orbicularis myectomy provides early symptom relief and durable cosmetic improvement, but its functional effect tends to decline over time. Minimally invasive techniques may help reduce complications while maintaining efficacy.

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Journal
Ophthalmic Plastic and Reconstructive Surgery
Published
2026-05-27
DOI
https://doi.org/10.1097/iop.0000000000003232
Primary Topic
Botulinum Toxin and Related Neurological Disorders
Type
article
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article

Surgical Management of Essential Blepharospasm: Long-Term Results After Orbicularis Myectomy

M. Callet, S. AZRIA, Yanice Chaoui-Boudghane, Olivier Galatoire et al.
Ophthalmic Plastic and Reconstructive Surgery
Botulinum Toxin and Related Neurological Disorders
article

Surgical Management of Essential Blepharospasm: Long-Term Results After Orbicularis Myectomy

M. Callet, S. AZRIA, Yanice Chaoui-Boudghane, Olivier Galatoire, Maria Cristiana Cazacu
article en

Abstract

PURPOSE: To evaluate the long-term functional and aesthetic outcomes of orbicularis myectomy in patients with medically refractory benign essential blepharospasm and to contextualize findings within current surgical literature. METHODS: A retrospective analysis was conducted on 80 patients (129 eyelids) who underwent subtotal orbicularis myectomy between 2014 and 2023. Bilateral procedures were performed sequentially. Mean follow-up was 84 months (range: 24-144.3). Surgery was offered after failure of initial botulinum toxin injections, with a mean delay of 18.5 months. RESULTS: At 6 and 12 months postoperatively, 72% of patients experienced functional improvement, with a mean 53% reduction in spasm severity. However, only 41% maintained long-term benefit. Spasms recurred in 86%, and only 7.5% achieved complete resolution without further botulinum toxin injections. Aesthetic outcomes were favorable in 96% of cases and remained stable over time. The frequency of botulinium toxin injections decreased from 1 every 3 months to every 4 months, though this change was not statistically significant (p = 0.12). Botulinum toxin dose was significantly reduced at 12 months (p < 0.001), but not at final follow-up (p = 0.2872), suggesting a temporary postoperative benefit. No major complications were observed. Transient lagophthalmos occurred in 3% of cases; 1 case required surgical revision. There was no significant association between long-term disabling symptoms and age (p = 0.61), gender (p = 0.12), or active smoking (p = 0.49). CONCLUSION: Orbicularis myectomy provides early symptom relief and durable cosmetic improvement, but its functional effect tends to decline over time. Minimally invasive techniques may help reduce complications while maintaining efficacy.

Ophthalmic Plastic and Reconstructive Surgery
Fondation de Rothschild (FR)
Good health and well-being
Openalex Percentile: Top 6%
Botulinum Toxin and Related Neurological Disorders
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Surgical Management of Essential Blepharospasm: Long-Term Results After Orbicularis Myectomy — M. Callet, S. AZRIA, et al. · Ophthalmic Plastic and Reconstructive Surgery (2026) | TGRS Research Map | TGRS