Hypnosis on Perioperative Outcomes Among Patients Undergoing Non-Cardiovascular Surgeries: A Systematic Review of Randomized Trials

Surgery is a disturbing factor of perioperative outcomes in surgical patients. This study aims to explore the effects of clinical hypnosis in diverse perioperative disturbances among non-cardiovascular surgical patients. This is a systematic review according to PRISMA guidelines, using following databases: Cochrane trials, Scopus, Web of Science, Medline and Google Scholar with various keywords in English and French. Studies quality was assessed using Cochrane Rob 2 tool. Thirty randomized controlled trials published between 2012 and January 2025 were included in this review. Results showed that clinical hypnosis revealed a significant effect on decreasing pre and intraoperative anxiety, medication consumption especially opioids and hypnotics intra and postoperatively, risk of postoperative nausea and vomiting was also decreased in hypnosis group. A higher level of prolactin was also observed in women on post-cesarean section. Hypnosis is an interesting perioperative strategy, particularly in decreasing preoperative anxiety and medication consumption. Its impact on pain is uncertain and it can be related to techniques, patient hypnotic profile or type of surgery.