Catatonia Associated With First-Time Psilocybin Exposure: A Case Report

In this case report, we highlight a 28-year-old male patient with predominantly retarded type of catatonia following a single incidence of psilocybin ingestion. This patient presented with a history of six months of mutism and inability to feed himself after consuming psilocybin for the first time. He did not have any history of psychiatric illness or substance use. Imaging and laboratory results were unremarkable. The goal of this case report is to document one of the earliest records of psilocybin-induced catatonia.

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Publication Details

Journal
Cureus
Published
2026-05-27
DOI
https://doi.org/10.7759/cureus.c439
Primary Topic
Psychedelics and Drug Studies
Type
article
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0.00
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article

Catatonia Associated With First-Time Psilocybin Exposure: A Case Report

Jasbir Singh, Pranathi Mruthyunjaya
Cureus
Psychedelics and Drug Studies
article

Catatonia Associated With First-Time Psilocybin Exposure: A Case Report

Jasbir Singh, Pranathi Mruthyunjaya
article en

Abstract

In this case report, we highlight a 28-year-old male patient with predominantly retarded type of catatonia following a single incidence of psilocybin ingestion. This patient presented with a history of six months of mutism and inability to feed himself after consuming psilocybin for the first time. He did not have any history of psychiatric illness or substance use. Imaging and laboratory results were unremarkable. The goal of this case report is to document one of the earliest records of psilocybin-induced catatonia.

Cureus
Openalex Percentile: Top 4%
Psychedelics and Drug Studies
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