Head of the Syrian Hamster (Mesocricetus auratus): Planar Anatomy with Correlative Micro-Computed Tomography and Magnetic Resonance Imaging

Syrian hamsters (SHs) are widely used in research and as pets. However, their head anatomy has not yet been evaluated using sectional anatomy and imaging despite their unique features, which are important for studying ischemia–reperfusion injury, cancer, oral tumors, and common stomatognathic and ocular conditions. This study was conducted to correlate the planar anatomy of the heads of eight healthy male and female SHs with micro-CT and MRI images to establish a descriptive, imaging-based anatomical reference. Clinically important head structures observed in transverse, dorsal, and sagittal anatomical sections were correspondingly identified on micro-CT and/or MRI images. In SHs, head micro-CT was shown to be particularly effective for visualizing mineralized structures (e.g., dental and osseous tissues) and air-filled cavities (e.g., the ear canal and tympanic bulla), whereas MRI was demonstrated to provide superior assessment of soft tissues, including the brain, vertebral canal and spinal cord, musculature, intervertebral disks, major salivary glands, eye, and harderian and extraorbital lacrimal glands. The present investigation provides a descriptive and imaging-based anatomical reference of the SH head by integrating anatomical sections, in situ topographical anatomy, and dry-skull photographs with micro-CT and MRI datasets, thereby serving as a foundational resource for the interpretation of cross-sectional imaging in both research and clinical contexts.