Repeatability and Reliability of BioMetaTest Diagnostics

This article presents a preliminary pilot study on the repeatability and reliability of the BioMetaTest diagnostic system developed by Daphne Lab®, based on the proprietary MX Palladium technology. The research was originally conducted in 2009 by AIAS Afragola under the sponsorship of ASL Napoli 3 – Primary Care Department, and methodologically revised in 2026 for statistical reorganization and scientific dissemination. The study included 2,500 measurements obtained from 50 subjects undergoing 50 repeated evaluations under full blinding conditions. The main objective was to verify the intra-patient repeatability and inter-patient reliability of the BioMetaTest system, comparing its results with alternative bioelectronic systems and with a randomized control model. The results showed that 94% of the measurements remained within the maximum statistical error threshold of 10%, defined as an absolute acceptance criterion in accordance with principles inspired by ISO 9000, ISO/IEC 17025, and ISO 5725 standards. The comparative analysis demonstrated lower statistical variability in the Daphne Lab system compared to benchmark models, suggesting a high internal stability of the method. The work also addresses methodological aspects related to the statistical validation of technologies used in non-conventional medicine and naturopathy, proposing a reference framework applicable to diagnostic systems that still lack consolidated regulatory standards. This publication is intended for scientific dissemination purposes and does not aim to establish definitive clinical conclusions. The authors emphasize the need for additional multicenter studies to expand the dataset and confirm future research directions.