Challenges in Managing Undiagnosed Prenatal Sacrococcygeal Teratoma—Case Report and Literature Review

Background/Objectives: Teratomas of the sacrococcygeal region are rare, but the most common tumors found in fetuses. They develop from the three germ layers—mesoderm, ectoderm, and endoderm—and occur at a rate of 1 in 27,000 to 1 in 40,000, with a fourfold higher incidence in female fetuses. 63.9–74% of sacrococcygeal teratomas are detected prenatally, most often in the second trimester. Methods: This study reports the case of a woman in her second pregnancy at 29 weeks and 2 days gestation who was incidentally diagnosed with tumor-like lesion in the sacrococcygeal region of fetus. The clinical situation required the pregnancy to be delivered by emergency cesarean section, and the tumor was surgically removed within the first few days of life. The lesion was finally diagnosed as an immature teratoma, and appropriate management was initiated, resulting in stabilization of the child’s general condition and proper development. Results: Detailed imaging and characterization of the lesion are essential for determining the appropriate management and minimizing foreseeable obstetric and neonatal complications. Fetal echocardiography in cases of suspected teratoma in the sacrococcygeal region is essential for identifying life-threatening risk factors and influences the planning of further management. The choice of treatment depends on the clinical situation; among intrauterine interventions and pharmacological therapy, it has been demonstrated that surgical removal of the lesion within the first days of life reduces the risk of recurrence. Conclusions: In any case where lesion such as tumor of the sacrococcygeal region of fetus is suspected, the pregnant woman should be managed at a tertiary care center to ensure multidisciplinary care involving obstetricians, neonatologists, pediatric surgeons, and oncologists. This study provides a review of the literature on methods of diagnosis and treatment of sacrococcygeal teratomas in fetuses. It emphasizes the importance of accurate diagnosis and prenatal care in such cases and their impact on further management.