Ubiquinol: what midwives need to know

Mitochondrial function and oxidative balance are increasingly recognised as key determinants of fertility, pregnancy outcomes and reproductive ageing. Ubiquinol, the reduced and biologically active form of coenzyme Q10, plays a central role in these functions. Although synthesised endogenously, ubiquinol production may be insufficient during periods of heightened metabolic demand, oxidative stress or advancing maternal age. This article reviews the role of ubiquinol during reproductive life stages and outlines its relevance to midwifery knowledge and practice. Evidence from human and animal studies is included to provide mechanistic and clinical context. Although further research is needed to establish intake recommendations and long-term clinical relevance, understanding the physiological functions of ubiquinol may assist midwives in supporting women who are planning pregnancy, experiencing fertility challenges or conceiving at older ages.

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Publication Details

Journal
British Journal of Midwifery
Published
2026-05-27
DOI
https://doi.org/10.12968/bjom.2026.0011
Primary Topic
Coenzyme Q10 studies and effects
Type
article
Field-Weighted Citation Impact
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article

Ubiquinol: what midwives need to know

Emma Derbyshire
British Journal of Midwifery
Coenzyme Q10 studies and effects
article

Ubiquinol: what midwives need to know

Emma Derbyshire
article en

Abstract

Mitochondrial function and oxidative balance are increasingly recognised as key determinants of fertility, pregnancy outcomes and reproductive ageing. Ubiquinol, the reduced and biologically active form of coenzyme Q10, plays a central role in these functions. Although synthesised endogenously, ubiquinol production may be insufficient during periods of heightened metabolic demand, oxidative stress or advancing maternal age. This article reviews the role of ubiquinol during reproductive life stages and outlines its relevance to midwifery knowledge and practice. Evidence from human and animal studies is included to provide mechanistic and clinical context. Although further research is needed to establish intake recommendations and long-term clinical relevance, understanding the physiological functions of ubiquinol may assist midwives in supporting women who are planning pregnancy, experiencing fertility challenges or conceiving at older ages.

British Journal of MidwiferyVol. 34(6)
Insight (China) (CN), Nutritional Research Foundation (US)
Openalex Percentile: Top 9%
Coenzyme Q10 studies and effects
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Ubiquinol: what midwives need to know — Emma Derbyshire · British Journal of Midwifery (2026) | TGRS Research Map | TGRS