Biobank analysis reveals more than 88,000 genetic associations with metabolic traits

An investigation of the Estonian Biobank and the UK Biobank has identified more than 88,000 associations between more than 8,000 genomic regions and metabolic traits. The combined size of the sample enabled the detection of many more associations than in previous efforts. The study has enabled the discovery of associations with genetic variants present in only 1 in 10,000 individuals.

Publication Details

Journal
Nature
Published
2026-05-27
DOI
https://doi.org/10.1038/d41586-026-01571-z
Primary Topic
Genetic Associations and Epidemiology
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Biobank analysis reveals more than 88,000 genetic associations with metabolic traits

Nature
Genetic Associations and Epidemiology
article

Biobank analysis reveals more than 88,000 genetic associations with metabolic traits

article en

Abstract

An investigation of the Estonian Biobank and the UK Biobank has identified more than 88,000 associations between more than 8,000 genomic regions and metabolic traits. The combined size of the sample enabled the detection of many more associations than in previous efforts. The study has enabled the discovery of associations with genetic variants present in only 1 in 10,000 individuals.

Nature
Openalex Percentile: Top 6%
Genetic Associations and Epidemiology
DOIOpen Access PDFOpenAlex
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.