Beyond reproduction: The ovary as a systemic regulator of female health and aging

Classifying ovaries solely as reproductive organs has obscured their role as systemic regulators of female physiology. This Perspective makes the case that ovarian aging is a primary determinant of healthspan and belongs at the center of geroscience.

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Publication Details

Journal
PLoS Biology
Published
2026-05-27
DOI
https://doi.org/10.1371/journal.pbio.3003800
Primary Topic
Menopause: Health Impacts and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Beyond reproduction: The ovary as a systemic regulator of female health and aging

Jennifer L. Garrison
PLoS Biology
Menopause: Health Impacts and Treatments
article

Beyond reproduction: The ovary as a systemic regulator of female health and aging

Jennifer L. Garrison
article en

Abstract

Classifying ovaries solely as reproductive organs has obscured their role as systemic regulators of female physiology. This Perspective makes the case that ovarian aging is a primary determinant of healthspan and belongs at the center of geroscience.

PLoS BiologyVol. 24(5)
University of California, San Francisco (US)
Gender equality
Openalex Percentile: Top 7%
Menopause: Health Impacts and Treatments
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