Large-scale network distribution of resting-state functional abnormalities in chronic kidney disease and their relation to cognitive impairment

• CKD showed widespread resting-state functional abnormalities. • Abnormal voxels were concentrated in the DMN and FPN. • DMN was most affected, with FPN also prominently involved. • Lower haematocrit was linked to worse cognition via reduced IPL ALFF.

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Publication Details

Journal
Brain Research Bulletin
Published
2026-05-27
DOI
https://doi.org/10.1016/j.brainresbull.2026.111969
Primary Topic
Dialysis and Renal Disease Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Large-scale network distribution of resting-state functional abnormalities in chronic kidney disease and their relation to cognitive impairment

L J Zhang, H B Chen, Yun Fei Wang, Xiang Kong et al.
Brain Research Bulletin
Dialysis and Renal Disease Management
article

Large-scale network distribution of resting-state functional abnormalities in chronic kidney disease and their relation to cognitive impairment

L J Zhang, H B Chen, Yun Fei Wang, Xiang Kong, Yu Ting Yang
article en

Abstract

• CKD showed widespread resting-state functional abnormalities. • Abnormal voxels were concentrated in the DMN and FPN. • DMN was most affected, with FPN also prominently involved. • Lower haematocrit was linked to worse cognition via reduced IPL ALFF.

Brain Research BulletinVol. 241
Hainan General Hospital (CN), Second Affiliated Hospital of Nanjing Medical University (CN), Hainan Medical University (CN), Nanjing Medical University (CN), Nanjing University (CN)
Openalex Percentile: Top 7%
Dialysis and Renal Disease Management
DOIOpen Access PDFOpenAlex
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