Large Cutaneous Mixed Tumor of Apocrine Type Formerly Known As Chondroid Syringoma: A Case Report

Large subcutaneous masses are relatively uncommon and usually benign. Lipomatous tumors predominate and are typically nonmalignant; however, atypical lipomatous tumors and liposarcomas can occur. Although malignancy is uncommon overall, soft tissue sarcomas may present as large or deep subcutaneous masses. A woman in her 50s presented to the primary care clinic with a large, firm, and mobile mass on the posterior aspect of the left shoulder that had been present for seven years. After excisional biopsy, pathological evaluation confirmed the diagnosis of cutaneous mixed tumor, apocrine type (chondroid syringoma). Cutaneous mixed tumor is a rare and typically benign neoplasm that can arise from either eccrine or apocrine glands and typically presents as a slow-growing, painless nodule. Definitive management and treatment involve surgical excision with a goal of removal of the entire tumor to avoid both recurrence and rare instances of malignant transformation.

Authors

Publication Details

Journal
Cureus
Published
2026-05-27
DOI
https://doi.org/10.7759/cureus.109772
Primary Topic
Cancer and Skin Lesions
Type
article
Field-Weighted Citation Impact
0.00
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article

Large Cutaneous Mixed Tumor of Apocrine Type Formerly Known As Chondroid Syringoma: A Case Report

Eva Bernstein, Morteza Khodaee, John J Fowler
Cureus
Cancer and Skin Lesions
article

Large Cutaneous Mixed Tumor of Apocrine Type Formerly Known As Chondroid Syringoma: A Case Report

Eva Bernstein, Morteza Khodaee, John J Fowler
article en

Abstract

Large subcutaneous masses are relatively uncommon and usually benign. Lipomatous tumors predominate and are typically nonmalignant; however, atypical lipomatous tumors and liposarcomas can occur. Although malignancy is uncommon overall, soft tissue sarcomas may present as large or deep subcutaneous masses. A woman in her 50s presented to the primary care clinic with a large, firm, and mobile mass on the posterior aspect of the left shoulder that had been present for seven years. After excisional biopsy, pathological evaluation confirmed the diagnosis of cutaneous mixed tumor, apocrine type (chondroid syringoma). Cutaneous mixed tumor is a rare and typically benign neoplasm that can arise from either eccrine or apocrine glands and typically presents as a slow-growing, painless nodule. Definitive management and treatment involve surgical excision with a goal of removal of the entire tumor to avoid both recurrence and rare instances of malignant transformation.

Cureus
Openalex Percentile: Top 6%
Cancer and Skin Lesions
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