Idiopathic Scrotal Calcinosis in Young Adults: Two Case Reports

Idiopathic scrotal calcinosis (ISC) is a rare benign condition characterized by the gradual development of multiple painless calcified nodules confined to the scrotal skin. Although its exact origin remains poorly understood, several pathogenic mechanisms have been proposed, and its etiology continues to be debated. We report two cases of ISC in young adult males presenting with slowly progressive scrotal nodules, highlighting the characteristic clinical features of this uncommon entity, the role of surgical excision as definitive treatment, and the importance of histopathological examination in establishing the diagnosis.

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Publication Details

Journal
Cureus
Published
2026-05-23
DOI
https://doi.org/10.7759/cureus.109499
Primary Topic
Inflammatory Myopathies and Dermatomyositis
Type
article
Field-Weighted Citation Impact
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article

Idiopathic Scrotal Calcinosis in Young Adults: Two Case Reports

Mounir Jamali, Bouzid Balla, Soufiane Laknizi
Cureus
Inflammatory Myopathies and Dermatomyositis
article

Idiopathic Scrotal Calcinosis in Young Adults: Two Case Reports

Mounir Jamali, Bouzid Balla, Soufiane Laknizi
article en

Abstract

Idiopathic scrotal calcinosis (ISC) is a rare benign condition characterized by the gradual development of multiple painless calcified nodules confined to the scrotal skin. Although its exact origin remains poorly understood, several pathogenic mechanisms have been proposed, and its etiology continues to be debated. We report two cases of ISC in young adult males presenting with slowly progressive scrotal nodules, highlighting the characteristic clinical features of this uncommon entity, the role of surgical excision as definitive treatment, and the importance of histopathological examination in establishing the diagnosis.

Cureus
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Inflammatory Myopathies and Dermatomyositis
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