Depigmentation Outcomes in Pigmented Oral Lichen Planus Managed With Mycophenolate Mofetil

ABSTRACT Pigmented oral lichen planus (OLP) is a chronic, immune‐mediated mucosal disorder associated with dark black or brown discoloration secondary to the excess melanin deposition. This medical condition is often accompanied by the typical white (reticular) or red (erosive) OLP features and is refractory to conventional therapy. We report a case of OLP which was successfully managed with oral mycophenolate mofetil (MMF), resulting in significant symptomatic relief and reduction of hyperpigmentation. MMF offers a safe and effective systemic option for persistent pigmented OLP.

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Publication Details

Journal
Clinical Case Reports
Published
2026-05-22
DOI
https://doi.org/10.1002/ccr3.72765
Primary Topic
Oral Health Pathology and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Depigmentation Outcomes in Pigmented Oral Lichen Planus Managed With Mycophenolate Mofetil

Noureen Nahar, Atul Anand Bajoria, Pallawi Sinha, Jitendra Sharan et al.
Clinical Case Reports
Oral Health Pathology and Treatment
article

Depigmentation Outcomes in Pigmented Oral Lichen Planus Managed With Mycophenolate Mofetil

Noureen Nahar, Atul Anand Bajoria, Pallawi Sinha, Jitendra Sharan, Tania Biswas, Smriti K. C. Basynat
article en

Abstract

ABSTRACT Pigmented oral lichen planus (OLP) is a chronic, immune‐mediated mucosal disorder associated with dark black or brown discoloration secondary to the excess melanin deposition. This medical condition is often accompanied by the typical white (reticular) or red (erosive) OLP features and is refractory to conventional therapy. We report a case of OLP which was successfully managed with oral mycophenolate mofetil (MMF), resulting in significant symptomatic relief and reduction of hyperpigmentation. MMF offers a safe and effective systemic option for persistent pigmented OLP.

Clinical Case ReportsVol. 14(6)
All India Institute of Medical Sciences Bhubaneswar (IN), Hi-Tech Medical College & Hospital (IN), Kathmandu University (NP), KIIT University (IN)
Openalex Percentile: Top 5%
Oral Health Pathology and Treatment
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