VITAMIN D LEVEL AND ITS RELATIONSHIP WITH CYTOKINE LEVEL IN BRONCHO-OBSTRUCTIVE SYNDROME IN CHILDREN

VITAMIN D LEVEL AND ITS RELATIONSHIP WITH CYTOKINE LEVEL IN BRONCHO-OBSTRUCTIVE SYNDROME IN CHILDREN Turayeva Nafisa Omonovna Ph.D., Associate Professor, Samarkand State Medical University (Samarkand, Uzbekistan) Khamzaeva Kamina Azizovna Student of group 527, Faculty of Pediatrics, Samarkand State Medical University (Samarkand, Uzbekistan) https://doi.org/10.5281/zenodo.20338280 Abstract: The aim of the study was to investigate the effect of vitamin D on the course of broncho-obstructive syndrome in children and to determine its relationship with cytokine status. The study involved 86 patients aged 3 to 15 years with acute obstructive bronchitis, recurrent obstructive bronchitis and bronchial asthma. The patients underwent a single set of diagnostic studies: clinical examination, immunological examination, and a study of vitamin D levels in blood serum. The results of the study showed that vitamin D deficiency was accompanied by the development of secondary immune deficiency. Keywords: broncho-obstructive syndrome, vitamin D, immune status, children.