Anterior lumbar interbody fusion for degenerative lumbar disease: Outcomes and complications

Background: Anterior lumbar interbody fusion (ALIF) is a well-established option for selected patients with degenerative lumbar disease, but its complication profile remains a relevant concern in routine practice. This study aimed to evaluate complications and short-term pain improvement after ALIF in a consecutive institutional series. Methods: A retrospective consecutive case series of 39 adult patients who underwent ALIF between May 2021 and October 2025 was analyzed. Primary outcomes were postoperative complications and pain improvement assessed by visual analogue scale (VAS) scores. Secondary outcomes included intraoperative complications, operative time, blood loss, and length of stay. Results: Mean VAS score improved from 9.35 preoperatively to 3.71 postoperatively ( P < 0.0001). No vascular, dural, or nerve root injury occurred intraoperatively. Paresthesia was the most common complication (30.76%), followed by epidural hematoma (7.69%) and sympathetic changes (5.12%). No infection or reoperation was observed. Conclusion: ALIF provided significant short-term pain improvement with an overall favorable perioperative profile in this series.

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Publication Details

Journal
Surgical Neurology International
Published
2026-05-22
DOI
https://doi.org/10.25259/sni_386_2026
Primary Topic
Spine and Intervertebral Disc Pathology
Type
article
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article

Anterior lumbar interbody fusion for degenerative lumbar disease: Outcomes and complications

Reinaldo Rodrigues Pamplona, Vinicius Santos Baptista
Surgical Neurology International
Spine and Intervertebral Disc Pathology
article

Anterior lumbar interbody fusion for degenerative lumbar disease: Outcomes and complications

Reinaldo Rodrigues Pamplona, Vinicius Santos Baptista
article en

Abstract

Background: Anterior lumbar interbody fusion (ALIF) is a well-established option for selected patients with degenerative lumbar disease, but its complication profile remains a relevant concern in routine practice. This study aimed to evaluate complications and short-term pain improvement after ALIF in a consecutive institutional series. Methods: A retrospective consecutive case series of 39 adult patients who underwent ALIF between May 2021 and October 2025 was analyzed. Primary outcomes were postoperative complications and pain improvement assessed by visual analogue scale (VAS) scores. Secondary outcomes included intraoperative complications, operative time, blood loss, and length of stay. Results: Mean VAS score improved from 9.35 preoperatively to 3.71 postoperatively ( P < 0.0001). No vascular, dural, or nerve root injury occurred intraoperatively. Paresthesia was the most common complication (30.76%), followed by epidural hematoma (7.69%) and sympathetic changes (5.12%). No infection or reoperation was observed. Conclusion: ALIF provided significant short-term pain improvement with an overall favorable perioperative profile in this series.

Surgical Neurology InternationalVol. 17
Brain Research Foundation (US), Universidade Federal de São Paulo (BR)
Good health and well-being
Openalex Percentile: Top 5%
Spine and Intervertebral Disc Pathology
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