A Stromal-Centered Single-Cell Landscape Identifies POSTN <sup>+</sup> Fibroblasts as a High-Risk Stromal Subset in Hepatocellular Carcinoma
mCAFs as a transcriptionally distinct and functionally pro-tumorigenic stromal subset in HCC, supporting POSTN-centered stromal programs as candidate markers of aggressive tumor microenvironments and a basis for future mechanistic investigation.
Authors
- Yalin Chen (ORCID: https://orcid.org/0000-0002-4265-1018)
- Dong Wu
- Shichao Zhang
- Tingting Liu
Institutions
- Second Military Medical University (CN)
- The Fourth People's Hospital (CN)
- Eastern Hepatobiliary Surgery Hospital (CN)
Publication Details
- Journal
- Biomarkers
- Published
- 2026-05-22
- DOI
- https://doi.org/10.1080/1354750x.2026.2678877
- Primary Topic
- Cancer Cells and Metastasis
- Type
- article
- Field-Weighted Citation Impact
- 0.00