Contemporary Perioperative Outcomes of Robotic Retroperitoneal Lymph Node Dissection for Testicular Cancer

Introduction: Robotic retroperitoneal lymph node dissection (R-RPLND) is increasingly recognized as a treatment option for testicular cancer. This study reports contemporary perioperative outcomes from a single institution and examines national trends in R-RPLND adoption. Methods: We retrospectively reviewed patients who underwent R-RPLND at our institution between December 2022 and November 2024. Clinical and perioperative metrics were collected and analyzed using univariable statistical tests. National trends in R-RPLND utilization were assessed using data from the National Cancer Database from 2012 to 2021. Multivariable logistic regression was performed to evaluate factors associated with the use of R-RPLND. Results: At our institution, 31 men underwent R-RPLND. The average length of stay was 1.4 days, and the average estimated blood loss was 60.3 mL. The 30-day complication rate was 3.2%, representing one case of chylous ascites. Nationally, R-RPLND utilization increased from 2.5% in 2012 to 8.3% in 2021. Patients with stages II and III disease were less likely to receive robotic surgery compared to those with stage I disease (odds ratio [OR]: 0.383, 95% confidence interval [CI]: 0.167–0.880, p = 0.024 for stage II; OR: 0.231, 95% CI: 0.098–0.545, p = 0.001 for stage III). No 90-day mortality rate was observed in either cohort. Conclusion: R-RPLND demonstrates favorable perioperative outcomes at both institutional and national levels, with increasing utilization over the past decade. The minimally invasive approach may reduce the morbidity of open surgery and serve as an alternative to chemoradiation in early-stage testicular cancer in selected patients. Further studies are needed to evaluate long-term oncologic outcomes and cost-effectiveness.

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Journal
Journal of Endourology
Published
2026-05-21
DOI
https://doi.org/10.1177/08927790261451073
Primary Topic
Testicular diseases and treatments
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article
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article

Contemporary Perioperative Outcomes of Robotic Retroperitoneal Lymph Node Dissection for Testicular Cancer

Matthew Mossanen, Guilherme Garcia Barros, Vincent D'Andrea, Zhiyu Qian et al.
Journal of Endourology
Testicular diseases and treatments
article

Contemporary Perioperative Outcomes of Robotic Retroperitoneal Lymph Node Dissection for Testicular Cancer

Matthew Mossanen, Guilherme Garcia Barros, Vincent D'Andrea, Zhiyu Qian, alexander p. Cole, Kevin Zhangxu, Andrea Piccolini, Stephan Korn, Giuliano B. Guglielmetti, Timothy N. Clinton, Rafael F. Coelho, Quoc-Dien Trinh, Klara Pohl, Miguel Amer Mestre, Adam S. Kibel, Christopher J. Magnani, Hanna Zurl
article en

Abstract

Introduction: Robotic retroperitoneal lymph node dissection (R-RPLND) is increasingly recognized as a treatment option for testicular cancer. This study reports contemporary perioperative outcomes from a single institution and examines national trends in R-RPLND adoption. Methods: We retrospectively reviewed patients who underwent R-RPLND at our institution between December 2022 and November 2024. Clinical and perioperative metrics were collected and analyzed using univariable statistical tests. National trends in R-RPLND utilization were assessed using data from the National Cancer Database from 2012 to 2021. Multivariable logistic regression was performed to evaluate factors associated with the use of R-RPLND. Results: At our institution, 31 men underwent R-RPLND. The average length of stay was 1.4 days, and the average estimated blood loss was 60.3 mL. The 30-day complication rate was 3.2%, representing one case of chylous ascites. Nationally, R-RPLND utilization increased from 2.5% in 2012 to 8.3% in 2021. Patients with stages II and III disease were less likely to receive robotic surgery compared to those with stage I disease (odds ratio [OR]: 0.383, 95% confidence interval [CI]: 0.167–0.880, p = 0.024 for stage II; OR: 0.231, 95% CI: 0.098–0.545, p = 0.001 for stage III). No 90-day mortality rate was observed in either cohort. Conclusion: R-RPLND demonstrates favorable perioperative outcomes at both institutional and national levels, with increasing utilization over the past decade. The minimally invasive approach may reduce the morbidity of open surgery and serve as an alternative to chemoradiation in early-stage testicular cancer in selected patients. Further studies are needed to evaluate long-term oncologic outcomes and cost-effectiveness.

Journal of Endourology
Brigham and Women's Hospital (US), Harvard University (US), Universidade de São Paulo (BR), University of Pittsburgh Medical Center (US), Hospital Universitario Son Espases (ES)
Good health and well-being
Openalex Percentile: Top 4%
Testicular diseases and treatments
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