Dynamic Color Doppler Ultrasound Features of Cutaneous Mastocytoma at High and Ultra‐High Frequency

OBJECTIVE: This study aimed to identify B-mode and color Doppler features in mastocytoma cases, and to evaluate anatomical changes after a dynamic friction maneuver. METHODS: A review of the high- and ultra-high-frequency color Doppler ultrasound examinations that were performed before and after a friction maneuver in clinically confirmed mastocytomas. RESULTS: Twelve cases met the criteria. Clinical presentation revealed solitary red, brown, pink, or yellowish macules, papules, nodules, or plaques. B-mode ultrasound showed mild hypoechoic dermal thickening, which was more evident in the superficial dermis in 91.7% of cases and diffuse in one patient (8.3%). Color Doppler imaging showed no or mild vascularity. The lesion was rubbed with mild pressure using a tongue depressor. After the maneuver, an increase in the hypoechoic dermal thickening and the dermal vascularity was detected on color Doppler. CONCLUSION: B-mode and Doppler ultrasound can reveal an increased hypoechoic dermal thickening and dermal hypervascularity after a friction maneuver, which can support the diagnosis of mastocytoma.

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Publication Details

Journal
Journal of Ultrasound in Medicine
Published
2026-05-22
DOI
https://doi.org/10.1002/jum.70309
Primary Topic
Mast cells and histamine
Type
article
Field-Weighted Citation Impact
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article

Dynamic Color Doppler Ultrasound Features of Cutaneous Mastocytoma at High and Ultra‐High Frequency

Teresa Oranges, Valentina Dini, Corrado Tagliati, Andrea Sechi et al.
Journal of Ultrasound in Medicine
Mast cells and histamine
article

Dynamic Color Doppler Ultrasound Features of Cutaneous Mastocytoma at High and Ultra‐High Frequency

Teresa Oranges, Valentina Dini, Corrado Tagliati, Andrea Sechi, Ximena Wortsman, Angelo Valerio Marzano
article en

Abstract

OBJECTIVE: This study aimed to identify B-mode and color Doppler features in mastocytoma cases, and to evaluate anatomical changes after a dynamic friction maneuver. METHODS: A review of the high- and ultra-high-frequency color Doppler ultrasound examinations that were performed before and after a friction maneuver in clinically confirmed mastocytomas. RESULTS: Twelve cases met the criteria. Clinical presentation revealed solitary red, brown, pink, or yellowish macules, papules, nodules, or plaques. B-mode ultrasound showed mild hypoechoic dermal thickening, which was more evident in the superficial dermis in 91.7% of cases and diffuse in one patient (8.3%). Color Doppler imaging showed no or mild vascularity. The lesion was rubbed with mild pressure using a tongue depressor. After the maneuver, an increase in the hypoechoic dermal thickening and the dermal vascularity was detected on color Doppler. CONCLUSION: B-mode and Doppler ultrasound can reveal an increased hypoechoic dermal thickening and dermal hypervascularity after a friction maneuver, which can support the diagnosis of mastocytoma.

Journal of Ultrasound in Medicine
University of Pisa (IT), University of Miami (US), Pontificia Universidad Católica de Chile (CL), University of Milan (IT), Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT), Ospedale Santa Chiara (IT), Institute for Diagnostic Imaging and Research of the Skin and Soft Tissues (CL), Meyer Children's Hospital (IT), Istituti di Ricovero e Cura a Carattere Scientifico (IT), University of Chile (CL)
Openalex Percentile: Top 8%
Mast cells and histamine
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