Development of <i>Curcuma domestica</i> extract-loaded transferosomes and evaluation of their <i>in vitro</i> antibacterial, anti-inflammatory, and antioxidant activities
of 6.82 ± 0.01), exceeding those of free CDEE. The optimised formulation demonstrated significant anti-inflammatory effects (95.11% inhibition of protein denaturation) comparable to that of ibuprofen. Incorporation of CDEE into transfersomal nanovesicles significantly enhanced its in vitro antibacterial, antioxidant, and anti-inflammatory activities, highlighting its potential as an effective nanocarrier-based delivery system.
Authors
- Lolyta Fitri Mustanti (ORCID: https://orcid.org/0000-0001-6213-0087)
- Lia Laila (ORCID: https://orcid.org/0000-0002-9343-5518)
- Abdi Wira Septama (ORCID: https://orcid.org/0000-0002-6471-7735)
- Sofna Banjarnahor (ORCID: https://orcid.org/0000-0001-9604-200X)
- Sufitni Sufitni (ORCID: https://orcid.org/0009-0005-4639-891X)
- Ade Sri Rohani (ORCID: https://orcid.org/0000-0003-2940-7608)
- Fadli Mubaroq Nasution
- Madeline Hana Tasya Siburian
- Ibrahim Jantan (ORCID: https://orcid.org/0000-0001-9185-755X)
- Yuandani
- Wahrianto
Institutions
- Universitas Sumatera Utara (ID)
- National Agricultural Research and Innovation Centre (HU)
- National University of Malaysia (MY)
Publication Details
- Journal
- Journal of Microencapsulation
- Published
- 2026-05-22
- DOI
- https://doi.org/10.1080/02652048.2026.2669798
- Primary Topic
- Curcumin's Biomedical Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Universitas Sumatera Utara