CHANGES IN THE MORPHOLOGICAL STRUCTURES OF THE SPLEEN IN RATS WITH MILD SPINAL CORD INJURIES

The present article includes the results of a scientific study aimed at investigating the morphometric parameters of the spleen in 3-month- old rats with mild spinal injuries. Based on the obtained data, it should be noted that a comparative morphometric analysis on the 7th day after mild spinal cord contusion shows a gradual increase in white pulp atrophy and compensatory remodeling of the red pulp. This is manifested by a decrease in the proportion of white pulp on day 7 (39.3%), day 14 (35.4%), and day 21 (27.6%) compared to the control group (48.7%). The most significant changes are observed on the 21st day, when white pulp atrophy reaches its maximum and is accompanied by pronounced collagenization of the red pulp.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-05-22
DOI
https://doi.org/10.5281/zenodo.20346958
Primary Topic
Spinal Cord Injury Research
Type
article
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article

CHANGES IN THE MORPHOLOGICAL STRUCTURES OF THE SPLEEN IN RATS WITH MILD SPINAL CORD INJURIES

N.E Tuxsanova, Sh.B Barotova
Zenodo (CERN European Organization for Nuclear Research)
Spinal Cord Injury Research
article

CHANGES IN THE MORPHOLOGICAL STRUCTURES OF THE SPLEEN IN RATS WITH MILD SPINAL CORD INJURIES

N.E Tuxsanova, Sh.B Barotova
article en

Abstract

The present article includes the results of a scientific study aimed at investigating the morphometric parameters of the spleen in 3-month- old rats with mild spinal injuries. Based on the obtained data, it should be noted that a comparative morphometric analysis on the 7th day after mild spinal cord contusion shows a gradual increase in white pulp atrophy and compensatory remodeling of the red pulp. This is manifested by a decrease in the proportion of white pulp on day 7 (39.3%), day 14 (35.4%), and day 21 (27.6%) compared to the control group (48.7%). The most significant changes are observed on the 21st day, when white pulp atrophy reaches its maximum and is accompanied by pronounced collagenization of the red pulp.

Zenodo (CERN European Organization for Nuclear Research)
Bukhara State Medical Institute named after Abu Ali ibn Sino (UZ)
Openalex Percentile: Top 6%
Spinal Cord Injury Research
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