Endometrial Serous Carcinoma Arising From Adenomyosis

Endometrial serous carcinoma (ESC) is a high-grade and aggressive form of endometrial cancer. Its development in association with adenomyosis, a benign condition characterized by the presence of endometrial tissue within the myometrium, is rare and poorly understood. This case report discusses a postmenopausal woman diagnosed with uterine serous carcinoma arising from adenomyosis, highlighting diagnostic challenges, clinical management, and prognosis. A comprehensive review of the literature is included to offer a broader perspective on this unusual association.

Authors

Publication Details

Journal
Cureus
Published
2026-05-22
DOI
https://doi.org/10.7759/cureus.109441
Primary Topic
Endometriosis Research and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Endometrial Serous Carcinoma Arising From Adenomyosis

Maurice J. Berkowitz, Karo K. Arzoo
Cureus
Endometriosis Research and Treatment
article

Endometrial Serous Carcinoma Arising From Adenomyosis

Maurice J. Berkowitz, Karo K. Arzoo
article en

Abstract

Endometrial serous carcinoma (ESC) is a high-grade and aggressive form of endometrial cancer. Its development in association with adenomyosis, a benign condition characterized by the presence of endometrial tissue within the myometrium, is rare and poorly understood. This case report discusses a postmenopausal woman diagnosed with uterine serous carcinoma arising from adenomyosis, highlighting diagnostic challenges, clinical management, and prognosis. A comprehensive review of the literature is included to offer a broader perspective on this unusual association.

Cureus
Openalex Percentile: Top 5%
Endometriosis Research and Treatment
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