Synthetic study of <i>vic</i> -bromination of diarylacetylenes, easy purification and separation
E -Selective bromination for diphenylacetylene was established by using the combination of NBS and FeBr 3 in CH 2 Cl 2 . In addition, easy purification and separation from the crude product were found. When the crude product was treated with heptane, the E isomer could be recovered as a solid material by utilizing the difference in solubility. On the other hand, the Z isomer could be removed by filtration while remaining in solution.
Authors
- Hiyono Suzuki
- Yoshinori Suzuma
- Yuto Akai
- Akane Togo
- Hidehiko Kodama
- Kouichi Matsumoto (ORCID: https://orcid.org/0000-0003-2592-7403)
- Makoto Matsumoto
Publication Details
- Journal
- Beilstein Journal of Organic Chemistry
- Published
- 2026-05-22
- DOI
- https://doi.org/10.3762/bjoc.22.61
- Primary Topic
- Vanadium and Halogenation Chemistry
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Kindai University
- Kanazawa University
- Japan Society for the Promotion of Science