Interferometric image scanning microscopy enables label-free super-resolution imaging of live cells

By implementing the super-resolution principles of image scanning microscopy in coherent imaging, Küppers et al. introduced interferometric image scanning microscopy, achieving 120 nm label-free lateral resolution with minimal phototoxicity and offering a robust tool for long-term observation of intracellular dynamics.

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Publication Details

Journal
Light Science & Applications
Published
2026-05-21
DOI
https://doi.org/10.1038/s41377-026-02316-3
Primary Topic
Digital Holography and Microscopy
Type
article
Field-Weighted Citation Impact
0.00
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article

Interferometric image scanning microscopy enables label-free super-resolution imaging of live cells

Qianxi Liang, Ren Wei, Peng Xi
Light Science & Applications
Digital Holography and Microscopy
article

Interferometric image scanning microscopy enables label-free super-resolution imaging of live cells

Qianxi Liang, Ren Wei, Peng Xi
article en

Abstract

By implementing the super-resolution principles of image scanning microscopy in coherent imaging, Küppers et al. introduced interferometric image scanning microscopy, achieving 120 nm label-free lateral resolution with minimal phototoxicity and offering a robust tool for long-term observation of intracellular dynamics.

Light Science & ApplicationsVol. 15(1)
Peking University (CN)
Openalex Percentile: Top 5%
Digital Holography and Microscopy
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