Pancreatic squamous cell carcinoma – A rare presentation of neoplasia

Pancreatic cancer (PC) has high morbidity and mortality rates, with a five-year survival rate of less than 10%. Within this spectrum,squamous cell carcinoma (SCC) of the pancreas stands out as a rare and aggressive form, representing between 0.5% and 2% ofdiagnosed cases. This report describes the case of a patient in whom a lesion in the body of the pancreas was incidentally identified,and he underwent a body and tail pancreatectomy. The diagnosis of pancreatic SCC was confirmed through anatomopathologicalexamination, adjuvant treatment with the FOLFIRINOX regimen was carried out and, after eight months of outpatient follow-up,there was no evidence of recurrence or progression of the disease. The rarity of this neoplasm impacts its management, highlightingthe need for more research to improve diagnosis and treatment and, consequently, the prognosis of patients.

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Publication Details

Journal
Marmara medical journal
Published
2026-05-21
DOI
https://doi.org/10.5472/marumj.1955630
Primary Topic
Pancreatic and Hepatic Oncology Research
Type
article
Field-Weighted Citation Impact
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article

Pancreatic squamous cell carcinoma – A rare presentation of neoplasia

dos Santos Vm, Lister Santos, Bruna Pignataro, Camila Silva et al.
Marmara medical journal
Pancreatic and Hepatic Oncology Research
article

Pancreatic squamous cell carcinoma – A rare presentation of neoplasia

dos Santos Vm, Lister Santos, Bruna Pignataro, Camila Silva, Mariana Melo, Andressa Tedeschi
article en

Abstract

Pancreatic cancer (PC) has high morbidity and mortality rates, with a five-year survival rate of less than 10%. Within this spectrum,squamous cell carcinoma (SCC) of the pancreas stands out as a rare and aggressive form, representing between 0.5% and 2% ofdiagnosed cases. This report describes the case of a patient in whom a lesion in the body of the pancreas was incidentally identified,and he underwent a body and tail pancreatectomy. The diagnosis of pancreatic SCC was confirmed through anatomopathologicalexamination, adjuvant treatment with the FOLFIRINOX regimen was carried out and, after eight months of outpatient follow-up,there was no evidence of recurrence or progression of the disease. The rarity of this neoplasm impacts its management, highlightingthe need for more research to improve diagnosis and treatment and, consequently, the prognosis of patients.

Marmara medical journalVol. 39(2)
Armed Forces Hospital (SA), Hospital do Servidor Público Estadual (BR)
Good health and well-being
Openalex Percentile: Top 7%
Pancreatic and Hepatic Oncology Research
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