Imazalil at high plasma concentrations: implications for neutrophil immunophenotype

neutrophils. No changes in the percentage of neutrophils expressing the analyzed molecules were observed in the presence of testosterone. In conclusion, imazalil modulates the neutrophil immunophenotype, which may inhibit functions such as adhesion, migration, chemotaxis, and phagocytosis. Consequently, this may predispose individuals exposed to this compound to innate immunity disorders.

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Publication Details

Journal
Journal of Immunotoxicology
Published
2026-05-21
DOI
https://doi.org/10.1080/1547691x.2026.2672428
Primary Topic
Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Type
article
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article

Imazalil at high plasma concentrations: implications for neutrophil immunophenotype

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Neutrophil, Myeloperoxidase and Oxidative Mechanisms
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Imazalil at high plasma concentrations: implications for neutrophil immunophenotype

Wojciech Miltyk, Sławomir Wołczyński, Joanna Chociej-Stypułkowska, Agnieszka Iwaniuk, Marzena Garley, Agnieszka Żebrowska, Katarzyna Bielawska, Małgorzata Rusak, Luiza Czaczkowska, Dariusz Skarżyński, Barbara Pucelik, Jolanta Wrobel, Piotr Radziwon, Milena Dabrowska, Olga Diana Drezek, Wioletta Ratajczak-Wrona, Ewa Jablonska
article en

Abstract

neutrophils. No changes in the percentage of neutrophils expressing the analyzed molecules were observed in the presence of testosterone. In conclusion, imazalil modulates the neutrophil immunophenotype, which may inhibit functions such as adhesion, migration, chemotaxis, and phagocytosis. Consequently, this may predispose individuals exposed to this compound to innate immunity disorders.

Journal of ImmunotoxicologyVol. 23(1)
Medical University of Białystok (PL), Lukasiewicz Research Network - Krakow Institute of Technology (PL), InLife Institute of Animal Reproduction and Food Research, Polish Academy of Sciences (PL)
Zero hunger
Openalex Percentile: Top 9%
Neutrophil, Myeloperoxidase and Oxidative Mechanisms
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