Cervical spine myxoid liposarcoma in a 30-year-old male: a rare case report

Introduction and clinical importance: Myxoid liposarcoma (MLS) is a rare soft tissue sarcoma subtype, typically affecting adults. Spinal involvement is exceptionally uncommon, requiring careful diagnosis and management. We report a rare primary cervical spine case. Case presentation: A 30-year-old man came to the neurology clinic transferred from a general surgeon with weakness and stiffness in both legs after a biopsy of a deep neck mass. He came to the general surgeon with a history of neck swelling with mild dysphagia. Magnetic resonance imaging (MRI) showed a large mass from C5 to T3 with spinal curvature. The surgeons removed the tumor, which turned out to be primary MLS. The patient regained full leg movement after physiotherapy and is currently receiving adjuvant therapy. Clinical discussion: MLS develops from primitive mesenchymal cells rather than mature fat and can spread to unusual sites like the spine. MRI is valuable for diagnosis, and complete surgical removal is the main treatment, with radiotherapy or chemotherapy considered only when necessary. Conclusion: This case emphasizes considering MLS in deep cervical masses and the importance of early treatment significantly contributed to the patient’s full recovery.