Stable Function, Drifting Code: Robustness, Early Warning, and Dynamic Homeostasis in Clinical AI. Conceptual Note — URM / Dynamic Medicine Series

This Conceptual Note uses recent neuroscience research on representational drift as an evidence anchor for a broader systems principle in Dynamic Medicine and the Universal Resonance Model (URM): stable function does not require a fixed internal code. Stability may instead emerge from continuous regulated change. The paper argues that homeostasis should not be understood as stillness, but as regulated fluctuation. Robust biological systems preserve function by absorbing, dampening, redistributing, and neutralizing small perturbations before they become system-level transitions. In this framing, early-warning signals indicate weakening robustness before destabilization becomes clinically visible. The note also extends this reasoning to clinical AI. It argues that AI systems should not only classify visible disease states or detect transitions after they occur, but should help identify loss of absorptive capacity and dual drift between biological systems and model interpretation before clinical failure becomes apparent. This work is conceptual and does not present new empirical data. It is intended as a cross-domain evidence anchor linking representational drift, dynamic homeostasis, robustness, early-warning signals, and clinical AI governance within the URM framework.

Authors

Institutions

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-05-21
DOI
https://doi.org/10.5281/zenodo.20321185
Primary Topic
Embodied and Extended Cognition
Type
preprint
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
preprint

Stable Function, Drifting Code: Robustness, Early Warning, and Dynamic Homeostasis in Clinical AI. Conceptual Note — URM / Dynamic Medicine Series

Anita Domargård
Zenodo (CERN European Organization for Nuclear Research)
Embodied and Extended Cognition
preprint

Stable Function, Drifting Code: Robustness, Early Warning, and Dynamic Homeostasis in Clinical AI. Conceptual Note — URM / Dynamic Medicine Series

Anita Domargård
preprint en

Abstract

This Conceptual Note uses recent neuroscience research on representational drift as an evidence anchor for a broader systems principle in Dynamic Medicine and the Universal Resonance Model (URM): stable function does not require a fixed internal code. Stability may instead emerge from continuous regulated change. The paper argues that homeostasis should not be understood as stillness, but as regulated fluctuation. Robust biological systems preserve function by absorbing, dampening, redistributing, and neutralizing small perturbations before they become system-level transitions. In this framing, early-warning signals indicate weakening robustness before destabilization becomes clinically visible. The note also extends this reasoning to clinical AI. It argues that AI systems should not only classify visible disease states or detect transitions after they occur, but should help identify loss of absorptive capacity and dual drift between biological systems and model interpretation before clinical failure becomes apparent. This work is conceptual and does not present new empirical data. It is intended as a cross-domain evidence anchor linking representational drift, dynamic homeostasis, robustness, early-warning signals, and clinical AI governance within the URM framework.

Zenodo (CERN European Organization for Nuclear Research)
Swedish Rheumatism Association (SE)
Embodied and Extended Cognition
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.