ITU Tier 1+ #29: Developmental Biology (K_dev)

Tier 1+ Pass-1.5 paper 29 of 45. ITU-derived developmental biology on zygote + gastrulation + morphogenesis + differentiation + organogenesis. Defines K_dev = -log ρ_dev as the operator-algebraic modular Hamiltonian on H_zygote ⊗ H_gastrulation ⊗ H_morphogenesis ⊗ H_differentiation ⊗ H_organogenesis. K_dev inherits from K_QG via the CLPW 2023 type II crossed-product specialised to this scale. Numerical results. Turing 1952 morphogenesis, Yamanaka 2006 iPS Nobel 2012, organoids 2013 Lancaster, embryoid SHEEFS 2023. Topics covered. Turing 1952, Yamanaka iPS 2006, organoids Lancaster 2013, Magdalena Zernicka-Goetz embryoid 2023.6 SHEEFS, gene editing CRISPR Tessera 2024. 45-vertex polytope #29 top couplings: #5 K_cancer (0.92), #30 K_genome (0.92), #6 Aging (0.92), #27 Microbe (0.85). Ten falsifiable predictions: P_avg=0.66: arXiv 2026 (0.90 S), Human embryoid Phase 1 2030 (0.30 W), iPS therapies expand 2028 (0.65 M). Pass-2 roadmap: ~$1.6M: Dev analytics ($500K) + Lean Mathlib ($200K) + Embryology+iPS collab ($900K). Copyright © 2026 Munehiro Terada / Roboken. Licensed under CC-BY-4.0.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-05-19
DOI
https://doi.org/10.5281/zenodo.20280189
Primary Topic
Gene Regulatory Network Analysis
Type
preprint
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ITU Tier 1+ #29: Developmental Biology (K_dev)

Munehiro Terada
Zenodo (CERN European Organization for Nuclear Research)
Gene Regulatory Network Analysis
preprint

ITU Tier 1+ #29: Developmental Biology (K_dev)

Munehiro Terada
preprint en

Abstract

Tier 1+ Pass-1.5 paper 29 of 45. ITU-derived developmental biology on zygote + gastrulation + morphogenesis + differentiation + organogenesis. Defines K_dev = -log ρ_dev as the operator-algebraic modular Hamiltonian on H_zygote ⊗ H_gastrulation ⊗ H_morphogenesis ⊗ H_differentiation ⊗ H_organogenesis. K_dev inherits from K_QG via the CLPW 2023 type II crossed-product specialised to this scale. Numerical results. Turing 1952 morphogenesis, Yamanaka 2006 iPS Nobel 2012, organoids 2013 Lancaster, embryoid SHEEFS 2023. Topics covered. Turing 1952, Yamanaka iPS 2006, organoids Lancaster 2013, Magdalena Zernicka-Goetz embryoid 2023.6 SHEEFS, gene editing CRISPR Tessera 2024. 45-vertex polytope #29 top couplings: #5 K_cancer (0.92), #30 K_genome (0.92), #6 Aging (0.92), #27 Microbe (0.85). Ten falsifiable predictions: P_avg=0.66: arXiv 2026 (0.90 S), Human embryoid Phase 1 2030 (0.30 W), iPS therapies expand 2028 (0.65 M). Pass-2 roadmap: ~$1.6M: Dev analytics ($500K) + Lean Mathlib ($200K) + Embryology+iPS collab ($900K). Copyright © 2026 Munehiro Terada / Roboken. Licensed under CC-BY-4.0.

Zenodo (CERN European Organization for Nuclear Research)
Stroke Association (GB)
Gene Regulatory Network Analysis
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ITU Tier 1+ #29: Developmental Biology (K_dev) — Munehiro Terada · Zenodo (CERN European Organization for Nuclear Research) (2026) | TGRS Research Map | TGRS