Ultrasound-assisted 1,2,4-triazole Schiff bases: synthesis, characterization, docking, and dual inhibition of urease and α-glucosidase

AIM: This study aimed to design and synthesize novel 3-pentyl-substituted 1,2,4-triazole-5-thione Schiff base derivatives and evaluate their dual inhibitory potential against urease and α-glucosidase enzymes. MATERIALS AND METHODS: absorption, distribution, metabolism, and excretion (ADME) properties were predicted using SwissADME. RESULTS: . CONCLUSIONS: identified as a promising lead for further optimization.