Advancing Early‐Stage Type 1 Diabetes Care: Future Focused Pathways for Identification, Screening, Diagnosis, and Monitoring

ABSTRACT Background Although international guidelines provide recommendations for screening and monitoring of early‐stage type 1 diabetes (T1D), navigating the care pathway can still be difficult for individuals, caregivers, and healthcare professionals (HCPs). These challenges are exacerbated by variations in healthcare systems, gaps in communication, and limited psychosocial support. Aims This manuscript aims to bridge the gap between theory and clinical practice and present practical, stage‐specific recommendations for early‐stage T1D care in pediatric and adult populations. Materials and Methods This article was informed by a structured literature review, qualitative interviews with HCPs in the UK, Germany, France, Italy, and Spain, and multidisciplinary expert input from the CARE‐T1D working group. The group comprised six pediatric and six adult endocrinologists, and two psychologists from the EU, UK, and US. Results, Discussion and Conclusion Here we present proposed care pathways for pediatric and adult early‐stage T1D, integrating recommendations for clear communication, care coordination, and psychosocial support throughout. This manuscript is intended to support the standardization of early‐stage T1D detection and monitoring, thereby contributing to improved outcomes, including reducing the incidence of diabetic ketoacidosis (DKA) and hospitalization at stage 3 T1D diagnosis.

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Publication Details

Journal
Diabetes Obesity and Metabolism
Published
2026-05-18
DOI
https://doi.org/10.1111/dom.70688
Primary Topic
Diabetes and associated disorders
Type
article
Field-Weighted Citation Impact
0.00

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article

Advancing Early‐Stage Type 1 Diabetes Care: Future Focused Pathways for Identification, Screening, Diagnosis, and Monitoring

Diabetes Obesity and Metabolism
Diabetes and associated disorders
article

Advancing Early‐Stage Type 1 Diabetes Care: Future Focused Pathways for Identification, Screening, Diagnosis, and Monitoring

article en

Abstract

ABSTRACT Background Although international guidelines provide recommendations for screening and monitoring of early‐stage type 1 diabetes (T1D), navigating the care pathway can still be difficult for individuals, caregivers, and healthcare professionals (HCPs). These challenges are exacerbated by variations in healthcare systems, gaps in communication, and limited psychosocial support. Aims This manuscript aims to bridge the gap between theory and clinical practice and present practical, stage‐specific recommendations for early‐stage T1D care in pediatric and adult populations. Materials and Methods This article was informed by a structured literature review, qualitative interviews with HCPs in the UK, Germany, France, Italy, and Spain, and multidisciplinary expert input from the CARE‐T1D working group. The group comprised six pediatric and six adult endocrinologists, and two psychologists from the EU, UK, and US. Results, Discussion and Conclusion Here we present proposed care pathways for pediatric and adult early‐stage T1D, integrating recommendations for clear communication, care coordination, and psychosocial support throughout. This manuscript is intended to support the standardization of early‐stage T1D detection and monitoring, thereby contributing to improved outcomes, including reducing the incidence of diabetic ketoacidosis (DKA) and hospitalization at stage 3 T1D diagnosis.

Diabetes Obesity and Metabolism
Università Cattolica del Sacro Cuore (IT), Hôpital Necker-Enfants Malades (FR), Nottingham University Hospitals NHS Trust (GB), Vanderbilt University (US), Queen Elizabeth Hospital Birmingham (GB), Diabetes Australia (AU), Universitair Ziekenhuis Leuven (BE), Hospital Universitario La Paz (ES), Morristown Medical Center (US), Sanofi (France) (FR), University of California San Diego (US), Institut Necker Enfants Malades (FR), Rady Children's Hospital-San Diego (US), Hospital Universitario Virgen Macarena (ES), Ospedali Riuniti di Ancona (IT), Centre Hospitalier Sud Francilien (FR), University Hospital Leipzig (DE), C3I (United States) (US), Instituto de Biomedicina de Sevilla (ES), Stanford Medicine (US), Universidad de Sevilla (ES), Stanford University (US)
Sanofi
Openalex Percentile: Top 5%
Diabetes and associated disorders
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