Microsurgical denervation of the spermatic cord for chronic scrotal pain: a prospective pilot study

Abstract Background Microsurgical denervation of the spermatic cord (MDSC) is one of the lines of management of chronic orchialgia, but it has not been fully adopted by different centers. This article reviews a case series experience with a review of literature. Methods This study is a prospective pilot study evaluating the safety and efficacy of MDSC in the management of chronic scrotal pain refractory to conservative management. The study included 30 patients who underwent unilateral MDSC. Efficacy of the technique was evaluated by the degree of pain improvement using the Visual Analogue Scale (VAS) which was done preoperatively and 6 months postoperatively. Safety was assessed by reporting any perioperative complications. Available literature was reviewed looking at safety and efficacy of the technique. Results Twenty patients had complete pain resolution, 5 had a partial but significant resolution of their pain and the pain remained the same in two patients following MDSC. The VAS pain score significantly improved from a median (IQR) of 8.4 (7.0–9.0) to 1.1 (0–9.0) postoperatively ( p = 0.0029). No significant complications have been encountered in this study. Conclusions MDSC seems to be a safe and efficacious surgical option for the treatment of refractory chronic scrotal pain (CSP) and should be more widely adopted by specialist centers.

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Publication Details

Journal
African Journal of Urology
Published
2026-05-19
DOI
https://doi.org/10.1186/s12301-026-00582-6
Primary Topic
Male Reproductive Health Studies
Type
article
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article

Microsurgical denervation of the spermatic cord for chronic scrotal pain: a prospective pilot study

African Journal of Urology
Male Reproductive Health Studies
article

Microsurgical denervation of the spermatic cord for chronic scrotal pain: a prospective pilot study

article en

Abstract

Abstract Background Microsurgical denervation of the spermatic cord (MDSC) is one of the lines of management of chronic orchialgia, but it has not been fully adopted by different centers. This article reviews a case series experience with a review of literature. Methods This study is a prospective pilot study evaluating the safety and efficacy of MDSC in the management of chronic scrotal pain refractory to conservative management. The study included 30 patients who underwent unilateral MDSC. Efficacy of the technique was evaluated by the degree of pain improvement using the Visual Analogue Scale (VAS) which was done preoperatively and 6 months postoperatively. Safety was assessed by reporting any perioperative complications. Available literature was reviewed looking at safety and efficacy of the technique. Results Twenty patients had complete pain resolution, 5 had a partial but significant resolution of their pain and the pain remained the same in two patients following MDSC. The VAS pain score significantly improved from a median (IQR) of 8.4 (7.0–9.0) to 1.1 (0–9.0) postoperatively ( p = 0.0029). No significant complications have been encountered in this study. Conclusions MDSC seems to be a safe and efficacious surgical option for the treatment of refractory chronic scrotal pain (CSP) and should be more widely adopted by specialist centers.

African Journal of UrologyVol. 32(1)
Cairo University (EG), Tanta University Hospital (EG)
Good health and well-being
Openalex Percentile: Top 3%
Male Reproductive Health Studies
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