Costal synostosis mimicking supraclavicular lymphadenopathy in a breast cancer patient: A diagnostic pitfall

The discovery of a supraclavicular mass in patients with a history of breast cancer is highly suspicious for metastatic lymph node involvement. We report the case of a 68-year-old woman with a history of left breast carcinoma treated by mastectomy one year earlier. During routine follow-up, clinical examination revealed a firm mass in the left supraclavicular fossa suggestive of supraclavicular lymphadenopathy. Ultrasound examination showed a poorly defined structure with marked posterior acoustic shadowing, making characterization difficult. Further evaluation with computed tomography demonstrated a fusion between the first and second ribs consistent with costal synostosis. This anatomical variant explained the palpable supraclavicular prominence that clinically mimicked nodal disease. This case highlights a rare diagnostic pitfall and emphasizes the importance of cross-sectional imaging in differentiating benign anatomical variants from metastatic lymphadenopathy in oncologic patients.

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Publication Details

Journal
Radiology Case Reports
Published
2026-05-19
DOI
https://doi.org/10.1016/j.radcr.2026.04.054
Primary Topic
Bone Tumor Diagnosis and Treatments
Type
article
Field-Weighted Citation Impact
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article

Costal synostosis mimicking supraclavicular lymphadenopathy in a breast cancer patient: A diagnostic pitfall

Radiology Case Reports
Bone Tumor Diagnosis and Treatments
article

Costal synostosis mimicking supraclavicular lymphadenopathy in a breast cancer patient: A diagnostic pitfall

article en

Abstract

The discovery of a supraclavicular mass in patients with a history of breast cancer is highly suspicious for metastatic lymph node involvement. We report the case of a 68-year-old woman with a history of left breast carcinoma treated by mastectomy one year earlier. During routine follow-up, clinical examination revealed a firm mass in the left supraclavicular fossa suggestive of supraclavicular lymphadenopathy. Ultrasound examination showed a poorly defined structure with marked posterior acoustic shadowing, making characterization difficult. Further evaluation with computed tomography demonstrated a fusion between the first and second ribs consistent with costal synostosis. This anatomical variant explained the palpable supraclavicular prominence that clinically mimicked nodal disease. This case highlights a rare diagnostic pitfall and emphasizes the importance of cross-sectional imaging in differentiating benign anatomical variants from metastatic lymphadenopathy in oncologic patients.

Radiology Case ReportsVol. 21(8)
Mohamed I University (MA)
Good health and well-being
Openalex Percentile: Top 5%
Bone Tumor Diagnosis and Treatments
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