Whole-genome sequence of a varicella-zoster strain from an immunocompetent pediatric patient with severe herpes zoster

ABSTRACT We report the complete genome sequence of CGI, a strain of varicella-zoster virus (VZV) isolated from a 3-year-old immunocompetent patient with severe herpes zoster. The isolated strain exhibits an ORF62 genotype characteristic of vOka, in addition to a wild-type ORF0 gene and a novel methionine to valine substitution in ORF58.

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Journal
Microbiology Resource Announcements
Published
2026-05-18
DOI
https://doi.org/10.1128/mra.01123-25
Primary Topic
Herpesvirus Infections and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Whole-genome sequence of a varicella-zoster strain from an immunocompetent pediatric patient with severe herpes zoster

David C. Bloom, Alejandro Ortigas-Vásquez, Moriah L. Szpara, Charles Grose et al.
Microbiology Resource Announcements
Herpesvirus Infections and Treatments
article

Whole-genome sequence of a varicella-zoster strain from an immunocompetent pediatric patient with severe herpes zoster

David C. Bloom, Alejandro Ortigas-Vásquez, Moriah L. Szpara, Charles Grose, Mackenzie Shipley, Braylen V. Washington
article en

Abstract

ABSTRACT We report the complete genome sequence of CGI, a strain of varicella-zoster virus (VZV) isolated from a 3-year-old immunocompetent patient with severe herpes zoster. The isolated strain exhibits an ORF62 genotype characteristic of vOka, in addition to a wild-type ORF0 gene and a novel methionine to valine substitution in ORF58.

Microbiology Resource Announcements
University of Iowa (US), Pennsylvania State University (US), Center for Disease Dynamics, Economics & Policy (US), University of Florida (US), National Center for Ecological Analysis and Synthesis (US), Department of Virology (FR), Florida Agricultural and Mechanical University (US), Florida College (US)
Pennsylvania Department of Health, National Institutes of Health, National Science Foundation of Sri Lanka
Openalex Percentile: Top 6%
Herpesvirus Infections and Treatments
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