Draft genome of <i>Streptomyces globosus</i> OSY-MM, a broad-spectrum antimicrobial producer isolated from a cave in South Central Kentucky

ABSTRACT Streptomyces globosus OSY-MM was originally isolated from a soil sample collected from a cave in South Central Kentucky and was found to display strong, broad-spectrum antimicrobial activity. S. globosus OSY-MM has a 7,277,920 bp genome with 6,476 genes, including biosynthetic gene clusters encoding the production of streptothricin, kirromycin, and venezuelin-like antibiotics.

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Publication Details

Journal
Microbiology Resource Announcements
Published
2026-05-18
DOI
https://doi.org/10.1128/mra.00144-26
Primary Topic
Microbial Natural Products and Biosynthesis
Type
article
Field-Weighted Citation Impact
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article

Draft genome of Streptomyces globosus OSY-MM, a broad-spectrum antimicrobial producer isolated from a cave in South Central Kentucky

Ahmed E. Yousef, Zach L. Hawkins, Steven J. Carlson, Gabriella J. Gephart et al.
Microbiology Resource Announcements
Microbial Natural Products and Biosynthesis
article

Draft genome of Streptomyces globosus OSY-MM, a broad-spectrum antimicrobial producer isolated from a cave in South Central Kentucky

Ahmed E. Yousef, Zach L. Hawkins, Steven J. Carlson, Gabriella J. Gephart, Matthew J. Mezydlo, Ahmed G. Abdelhamid
article en

Abstract

ABSTRACT Streptomyces globosus OSY-MM was originally isolated from a soil sample collected from a cave in South Central Kentucky and was found to display strong, broad-spectrum antimicrobial activity. S. globosus OSY-MM has a 7,277,920 bp genome with 6,476 genes, including biosynthetic gene clusters encoding the production of streptothricin, kirromycin, and venezuelin-like antibiotics.

Microbiology Resource Announcements
The Ohio State University (US), Michigan State University (US)
Life in Land
Openalex Percentile: Top 7%
Microbial Natural Products and Biosynthesis
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