Low-Molecular-Weight Fraction of Ripe Pu-erh Tea Protects against Alcohol-Induced Gastric Injury via Gut Microbiota-Dependent Modulation
and increased butyrate production. Antibiotic-mediated microbiota depletion attenuated T3 efficacy, supporting a microbiota-dependent mechanism. Serum metabolomics further indicated regulation of glutathione-related pathways. Overall, T3 represents a promising low-molecular-weight fraction of Pu-erh tea for dietary prevention of AGI through modulation of microbiota-gut-stomach homeostasis.
Authors
- Ruisheng Li
- Sibo Zhao
- Li Luo (ORCID: https://orcid.org/0000-0002-4270-2671)
- Xingping Zhao (ORCID: https://orcid.org/0000-0003-1071-4683)
- Lijuan Chen (ORCID: https://orcid.org/0000-0003-3712-267X)
- Lifeng Dai
- Kaiyang Lu
- Xingli Guan
- Liang Zeng (ORCID: https://orcid.org/0000-0003-3860-7724)
- Yan Liu (ORCID: https://orcid.org/0000-0003-3677-9290)
- Mianhong Xu
- Jielin Jiang
Institutions
- Southwest University (CN)
- Sichuan Fine Arts Institute (CN)
- Yunnan Environmental Protection Bureau (CN)
- United Science (US)
- Institute for Fermentation (JP)
Publication Details
- Journal
- Journal of Agricultural and Food Chemistry
- Published
- 2026-05-18
- DOI
- https://doi.org/10.1021/acs.jafc.6c01237
- Primary Topic
- Alcohol Consumption and Health Effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fundamental Research Funds for the Central Universities
- Chongqing Graduate Student Research Innovation Project