Evaluation of Some Biochemical and Hematological Parameters in Experimentally Induced Diabetic Rats

Diabetes, defined by high blood sugar levels and glycosuria, is characterized by changes in insulin sensitivity, damage to the pancreas, and alterations in lipid and protein metabolism in advanced stages. In this study, 33 male Wistar albino rats were randomly divided into three groups: control, diabetes, and control+citric acid buffer. Blood samples for glucose control were taken from the rat's tail in all groups on days 0, 3, 6, 9, 16, 23, and 30, and from the heart under anesthesia after 4 weeks. Hematological and biochemical parameters were analyzed from blood and serum samples at the specified time intervals and at the end of the experiment, respectively.While chloride and CK levels decreased in the diabetes group compared to the control group (p

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Journal
Animal Health Production and Hygiene
Published
2026-05-18
DOI
https://doi.org/10.53913/aduveterinary.1840293
Primary Topic
Natural Antidiabetic Agents Studies
Type
article
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article

Evaluation of Some Biochemical and Hematological Parameters in Experimentally Induced Diabetic Rats

Beyza Suvarıklı Alan, Murat ALTINSOY, Feray Altan, Zafer Bulut et al.
Animal Health Production and Hygiene
Natural Antidiabetic Agents Studies
article

Evaluation of Some Biochemical and Hematological Parameters in Experimentally Induced Diabetic Rats

Beyza Suvarıklı Alan, Murat ALTINSOY, Feray Altan, Zafer Bulut, Rana Karçaaltıncaba
article en

Abstract

Diabetes, defined by high blood sugar levels and glycosuria, is characterized by changes in insulin sensitivity, damage to the pancreas, and alterations in lipid and protein metabolism in advanced stages. In this study, 33 male Wistar albino rats were randomly divided into three groups: control, diabetes, and control+citric acid buffer. Blood samples for glucose control were taken from the rat's tail in all groups on days 0, 3, 6, 9, 16, 23, and 30, and from the heart under anesthesia after 4 weeks. Hematological and biochemical parameters were analyzed from blood and serum samples at the specified time intervals and at the end of the experiment, respectively.While chloride and CK levels decreased in the diabetes group compared to the control group (p

Animal Health Production and HygieneVol. 15(2)
Selçuk University (TR), Dokuz Eylül Üniversitesi Hastanesi (TR)
Good health and well-being
Openalex Percentile: Top 6%
Natural Antidiabetic Agents Studies
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