Synthesis of Functionalized [5]-Cyclo- <i>m</i> -phenylenes Enabled by Controlled Multihalogenation Using a Carborane Catalyst
-[5]CMP served as a versatile handle for downstream derivatization. After benzylic bromination, diverse functional groups were introduced via nucleophilic substitution. Overall demethylation was achieved through the decarboxylation of the corresponding carboxylic acid.
Authors
- Koji Hirano (ORCID: https://orcid.org/0000-0001-9752-1985)
- Yuji Nishii (ORCID: https://orcid.org/0000-0002-6824-0639)
- Kohtaro Sugimoto
Institutions
- Osaka Gakuin University (JP)
- The University of Osaka (JP)
Publication Details
- Journal
- Organic Letters
- Published
- 2026-05-18
- DOI
- https://doi.org/10.1021/acs.orglett.6c01313
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Japan Society for the Promotion of Science
- Fusion Oriented REsearch for disruptive Science and Technology