Chronic Invasive Fungal Sinusitis Concerning for Sinonasal Malignancy With Unique Intracranial Extension

Chronic invasive fungal sinusitis is a rare sinonasal pathology characterized by histopathological evidence of fungi causing chronic inflammation, as well as radiologic imaging of bony destruction and extrasinus invasion. Here, the authors have described a case of chronic invasive fungal sinusitis with the presence of a fungal mass, orbital involvement, and intracranial extension into the anterior skull base. Management involved nasal endoscopy with biopsy, postoperative debridement, and antifungal therapy.

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Publication Details

Journal
The Permanente Journal
Published
2026-05-18
DOI
https://doi.org/10.7812/tpp/26.004
Primary Topic
Sinusitis and nasal conditions
Type
article
Field-Weighted Citation Impact
0.00
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article

Chronic Invasive Fungal Sinusitis Concerning for Sinonasal Malignancy With Unique Intracranial Extension

Cristian Gragnaniello, Erin M. Lopez, Margaret Scott, Philip Chen et al.
The Permanente Journal
Sinusitis and nasal conditions
article

Chronic Invasive Fungal Sinusitis Concerning for Sinonasal Malignancy With Unique Intracranial Extension

Cristian Gragnaniello, Erin M. Lopez, Margaret Scott, Philip Chen, Andrew Jung, Matthew Liu
article en

Abstract

Chronic invasive fungal sinusitis is a rare sinonasal pathology characterized by histopathological evidence of fungi causing chronic inflammation, as well as radiologic imaging of bony destruction and extrasinus invasion. Here, the authors have described a case of chronic invasive fungal sinusitis with the presence of a fungal mass, orbital involvement, and intracranial extension into the anterior skull base. Management involved nasal endoscopy with biopsy, postoperative debridement, and antifungal therapy.

The Permanente Journal
The University of Texas at San Antonio Health Science Center (US)
Good health and well-being
Openalex Percentile: Top 5%
Sinusitis and nasal conditions
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