Childhood adversity and benevolent childhood experiences associated with attenuated psychotic symptoms: The role of depression and anxiety

BACKGROUND: Psychotic Experiences (PEs) represent subclinical experiences that may precede psychotic disorders and reflect broader psychopathology. Guided by the affective pathway hypothesis, this study examined potential indirect effects of depression and anxiety on associations between adverse childhood experiences (ACEs), bullying, and PEs in adolescents. Secondary aims were to assess the role of benevolent childhood experiences (BCEs) and the influence of parental mental health. METHODS: Data were drawn from the Northern Ireland Youth Wellbeing Survey (N = 1299; aged 11-19 years). Using structural equation modelling (SEM) with bootstrapped standard errors, bullying, ACEs, BCEs, and parental psychological distress were entered as predictors of PEs through depression and anxiety latent variables. BCEs were modelled using linear and quadratic terms to test potential curvilinear protective effects. RESULTS: The SEM demonstrated good fit (Comparative fit index = 0.921, Tucker-Lewis index = 0.901, Root Mean Square Error of Approximation = 0.054, Standardized Root Mean Residual = 0.042). Bullying and ACEs significantly predicted higher depression and anxiety, while BCEs protective effects. Depression and anxiety significantly predicted PEs and served as indirect pathways linking bullying and ACEs to PEs. BCEs and parental distress demonstrated smaller protective and negative effects, respectively. CONCLUSIONS: Findings are consistent with the affective pathway to psychosis, suggesting early adversity may contribute to PEs via internalising symptoms. Depression showed the largest indirect association, underscoring the need for early detection and intervention targeting comorbid affective symptoms. Fostering benevolent experiences and adopting trauma-informed, intergenerational approaches may mitigate risk and strengthen resilience.

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Publication Details

Journal
Schizophrenia Research
Published
2026-05-18
DOI
https://doi.org/10.1016/j.schres.2026.05.010
Primary Topic
Child and Adolescent Psychosocial and Emotional Development
Type
article
Field-Weighted Citation Impact
0.00

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article

Childhood adversity and benevolent childhood experiences associated with attenuated psychotic symptoms: The role of depression and anxiety

Lisa Bunting, Ciaran Mullholand, Joshua Kearns, Ciaran Shannon et al.
Schizophrenia Research
Child and Adolescent Psychosocial and Emotional Development
article

Childhood adversity and benevolent childhood experiences associated with attenuated psychotic symptoms: The role of depression and anxiety

Lisa Bunting, Ciaran Mullholand, Joshua Kearns, Ciaran Shannon, Mark Shevlin, Gavin Davidson
article en

Abstract

BACKGROUND: Psychotic Experiences (PEs) represent subclinical experiences that may precede psychotic disorders and reflect broader psychopathology. Guided by the affective pathway hypothesis, this study examined potential indirect effects of depression and anxiety on associations between adverse childhood experiences (ACEs), bullying, and PEs in adolescents. Secondary aims were to assess the role of benevolent childhood experiences (BCEs) and the influence of parental mental health. METHODS: Data were drawn from the Northern Ireland Youth Wellbeing Survey (N = 1299; aged 11-19 years). Using structural equation modelling (SEM) with bootstrapped standard errors, bullying, ACEs, BCEs, and parental psychological distress were entered as predictors of PEs through depression and anxiety latent variables. BCEs were modelled using linear and quadratic terms to test potential curvilinear protective effects. RESULTS: The SEM demonstrated good fit (Comparative fit index = 0.921, Tucker-Lewis index = 0.901, Root Mean Square Error of Approximation = 0.054, Standardized Root Mean Residual = 0.042). Bullying and ACEs significantly predicted higher depression and anxiety, while BCEs protective effects. Depression and anxiety significantly predicted PEs and served as indirect pathways linking bullying and ACEs to PEs. BCEs and parental distress demonstrated smaller protective and negative effects, respectively. CONCLUSIONS: Findings are consistent with the affective pathway to psychosis, suggesting early adversity may contribute to PEs via internalising symptoms. Depression showed the largest indirect association, underscoring the need for early detection and intervention targeting comorbid affective symptoms. Fostering benevolent experiences and adopting trauma-informed, intergenerational approaches may mitigate risk and strengthen resilience.

Schizophrenia ResearchVol. 295
Queen's University Belfast (GB), University of Ulster (GB), Northern Health and Social Care Trust (GB)
Department for the Economy
Peace, Justice and strong institutions
Openalex Percentile: Top 4%
Child and Adolescent Psychosocial and Emotional Development
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