Csp <sup>3</sup> –H Bond Carbynoid Functionalization by Photoredox Catalysis
-H carbynoid functionalization of 1,3-dicarbonyl compounds with α-iodionium diazo compounds has been developed to rapidly assemble α,β-diacyl-α,β-unsaturated ketones. This protocol offers a straightforward approach to access β-deuterated-α,β-unsaturated carbonyl molecules via a 1,2-H shift process.
Authors
- Wei Zeng (ORCID: https://orcid.org/0000-0002-6113-2459)
- S S Chen
- J D Li
- Ying Xie (ORCID: https://orcid.org/0000-0002-0237-3244)
- Lixing Shen
- J S Peng
- Huanfeng Jiang (ORCID: https://orcid.org/0000-0002-4355-0294)
Institutions
- Key Laboratory of Guangdong Province (CN)
- Green Chemistry (PL)
- Sichuan University of Science and Engineering (CN)
- South China University of Technology (CN)
Publication Details
- Journal
- Organic Letters
- Published
- 2026-05-18
- DOI
- https://doi.org/10.1021/acs.orglett.6c01646
- Primary Topic
- Cyclopropane Reaction Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China