Core Emulating Optimization of Mycoleptodiscin A for Synthetically Tractable Antifungal Leads
on lettuce leaves. They could effectively inhibit oxalic acid production, damage the cell membrane, and cause mycelium deformation. The less complex drimane heterocycles can serve as promising and accessible models for the discovery of novel antifungal ingredients.
Authors
- Nvdan Hu
- F. L. Zhang (ORCID: https://orcid.org/0000-0002-8708-4846)
- Shengkun Li
- Xian Ming
- Shengxin Sun
Institutions
- Guizhou University (CN)
- Shanghai Pesticide Research Institute (CN)
- Guizhou Institute of Technology (CN)
Publication Details
- Journal
- Journal of Agricultural and Food Chemistry
- Published
- 2026-05-18
- DOI
- https://doi.org/10.1021/acs.jafc.5c14378
- Primary Topic
- Entomopathogenic Microorganisms in Pest Control
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Science and Technology Program of Guizhou Province