Capillaroscopic assessment of the nailfold in patients with rosacea

OBJECTIVE: Rosacea is a common chronic inflammatory dermatosis characterized by erythema, papules, pustules, and phymatous lesions in the central facial region. Evidence regarding the pathogenesis of rosacea suggests that microvascular changes may occur in affected individuals. This study aims to examine the relationship between capillaroscopic findings and disease characteristics, subgroups and Demodex infestation. MATERIAL AND METHODS: The study included a patient group of 50 individuals diagnosed with rosacea and a control group of 50 individuals without inflammatory diseases. Capillaroscopic evaluations were performed using a Dino-Lite Edge (P/N: AM7515MZT, Taiwan) digital capillaroscopy device, with the second to fifth nailfolds of both hands examined at ×200 magnification. RESULTS: = 0.295). CONCLUSION: Capillary irregularities, avascular areas, neovascularization, and tortuosity were observed at higher rates in patients with rosacea, suggesting these findings may reflect disease-associated peripheral microvascular alterations.

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Publication Details

Journal
Cutaneous and Ocular Toxicology
Published
2026-05-18
DOI
https://doi.org/10.1080/15569527.2026.2673153
Primary Topic
Acne and Rosacea Treatments and Effects
Type
article
Field-Weighted Citation Impact
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article

Capillaroscopic assessment of the nailfold in patients with rosacea

Mualla Polat, Tuna Sezer, Yasin Karaçöl
Cutaneous and Ocular Toxicology
Acne and Rosacea Treatments and Effects
article

Capillaroscopic assessment of the nailfold in patients with rosacea

Mualla Polat, Tuna Sezer, Yasin Karaçöl
article en

Abstract

OBJECTIVE: Rosacea is a common chronic inflammatory dermatosis characterized by erythema, papules, pustules, and phymatous lesions in the central facial region. Evidence regarding the pathogenesis of rosacea suggests that microvascular changes may occur in affected individuals. This study aims to examine the relationship between capillaroscopic findings and disease characteristics, subgroups and Demodex infestation. MATERIAL AND METHODS: The study included a patient group of 50 individuals diagnosed with rosacea and a control group of 50 individuals without inflammatory diseases. Capillaroscopic evaluations were performed using a Dino-Lite Edge (P/N: AM7515MZT, Taiwan) digital capillaroscopy device, with the second to fifth nailfolds of both hands examined at ×200 magnification. RESULTS: = 0.295). CONCLUSION: Capillary irregularities, avascular areas, neovascularization, and tortuosity were observed at higher rates in patients with rosacea, suggesting these findings may reflect disease-associated peripheral microvascular alterations.

Cutaneous and Ocular Toxicology
Hakkari University (TR), Bolu Abant İzzet Baysal University (TR)
Openalex Percentile: Top 5%
Acne and Rosacea Treatments and Effects
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