Appendiceal Neuroendocrine Tumor: A Case Report

Neuroendocrine tumors (NETs) are rare neoplasms that most commonly occur in the gastrointestinal tract, lungs, and pancreas but may arise anywhere where there are neuroendocrine cells within the body. When neuroendocrine tumors metastasize to the liver, patients present with carcinoid syndrome, a group of symptoms characterized by flushing, diarrhea, and right-sided heart disease. However, many NETs do not cause carcinoid syndrome, sometimes leading to a unique clinical presentation. Patients may present with symptoms of appendicitis, ovarian torsion, or be completely asymptomatic. We report a case of a 25-year-old male with a Grade 1 neuroendocrine tumor of the appendix, who underwent a laparoscopic appendectomy. Determining whether the NET has metastasized is crucial for proper long-term treatment of patients post-appendectomy.

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Publication Details

Journal
Advances in Clinical Medical Research and Healthcare Delivery
Published
2026-05-17
DOI
https://doi.org/10.53785/2769-2779.1378
Primary Topic
Intraperitoneal and Appendiceal Malignancies
Type
article
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article

Appendiceal Neuroendocrine Tumor: A Case Report

Thomas Russo, Mathew Devine, Daniel Zipfel
Advances in Clinical Medical Research and Healthcare Delivery
Intraperitoneal and Appendiceal Malignancies
article

Appendiceal Neuroendocrine Tumor: A Case Report

Thomas Russo, Mathew Devine, Daniel Zipfel
article en

Abstract

Neuroendocrine tumors (NETs) are rare neoplasms that most commonly occur in the gastrointestinal tract, lungs, and pancreas but may arise anywhere where there are neuroendocrine cells within the body. When neuroendocrine tumors metastasize to the liver, patients present with carcinoid syndrome, a group of symptoms characterized by flushing, diarrhea, and right-sided heart disease. However, many NETs do not cause carcinoid syndrome, sometimes leading to a unique clinical presentation. Patients may present with symptoms of appendicitis, ovarian torsion, or be completely asymptomatic. We report a case of a 25-year-old male with a Grade 1 neuroendocrine tumor of the appendix, who underwent a laparoscopic appendectomy. Determining whether the NET has metastasized is crucial for proper long-term treatment of patients post-appendectomy.

Advances in Clinical Medical Research and Healthcare DeliveryVol. 6(2)
Lake Erie College of Osteopathic Medicine (US)
Good health and well-being
Openalex Percentile: Top 6%
Intraperitoneal and Appendiceal Malignancies
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