Effectiveness of thermal radiofrequency ablation versus corticosteroid injections for pain reduction in facet-mediated chronic low back pain: a systematic review and meta-analysis

BACKGROUND: Facet joint syndrome (FJS) is a prevalent cause of chronic low back pain (CLBP), resulting in reduced quality of life. Radiofrequency ablation (RFA) and corticosteroid injections are commonly utilized; however, direct comparative evidence specific to lumbar FJS remains limited. METHODS: A comprehensive search of PubMed, Embase, Web of Science, Cochrane Library, and Scopus (from inception to November 2025) was conducted to identify randomized controlled trials (RCTs) evaluating thermal RFA versus corticosteroid injections. The primary outcome measured was the Visual Analog Scale (VAS) at 3- and 6-months. Review Manager 5.4 was used to evaluate mean differences (MD) across outcomes using a random-effects model. RESULT: < 0.00001), favoring RFA. Heterogeneity was moderate to low across timepoints. Although significant, these results fell underneath the minimally important clinical difference (MCID). CONCLUSION: In our study, thermal RFA provided greater pain reduction than corticosteroid injections for FJS causing CLBP, suggesting a modest short-term advantage in pain reduction.

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Journal
Pain Management
Published
2026-05-18
DOI
https://doi.org/10.1080/17581869.2026.2675483
Primary Topic
Spine and Intervertebral Disc Pathology
Type
article
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article

Effectiveness of thermal radiofrequency ablation versus corticosteroid injections for pain reduction in facet-mediated chronic low back pain: a systematic review and meta-analysis

Gilbert Siu, Jason Tran, Han Liu, Justin Le et al.
Pain Management
Spine and Intervertebral Disc Pathology
article

Effectiveness of thermal radiofrequency ablation versus corticosteroid injections for pain reduction in facet-mediated chronic low back pain: a systematic review and meta-analysis

Gilbert Siu, Jason Tran, Han Liu, Justin Le, Anish Rana, Andrew Atschinow, Lisa Huang, Brandon Lazar
article en

Abstract

BACKGROUND: Facet joint syndrome (FJS) is a prevalent cause of chronic low back pain (CLBP), resulting in reduced quality of life. Radiofrequency ablation (RFA) and corticosteroid injections are commonly utilized; however, direct comparative evidence specific to lumbar FJS remains limited. METHODS: A comprehensive search of PubMed, Embase, Web of Science, Cochrane Library, and Scopus (from inception to November 2025) was conducted to identify randomized controlled trials (RCTs) evaluating thermal RFA versus corticosteroid injections. The primary outcome measured was the Visual Analog Scale (VAS) at 3- and 6-months. Review Manager 5.4 was used to evaluate mean differences (MD) across outcomes using a random-effects model. RESULT: < 0.00001), favoring RFA. Heterogeneity was moderate to low across timepoints. Although significant, these results fell underneath the minimally important clinical difference (MCID). CONCLUSION: In our study, thermal RFA provided greater pain reduction than corticosteroid injections for FJS causing CLBP, suggesting a modest short-term advantage in pain reduction.

Pain Management
Health Net (US), Inspira Medical Center Vineland (US), Rowan University (US), University of Rochester (US)
Openalex Percentile: Top 7%
Spine and Intervertebral Disc Pathology
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Effectiveness of thermal radiofrequency ablation versus corticosteroid injections for pain reduction in facet-mediated chronic low back pain: a systematic review and meta-analysis — Gilbert Siu, Jason Tran, et al. · Pain Management (2026) | TGRS Research Map | TGRS