Effectiveness of thermal radiofrequency ablation versus corticosteroid injections for pain reduction in facet-mediated chronic low back pain: a systematic review and meta-analysis
BACKGROUND: Facet joint syndrome (FJS) is a prevalent cause of chronic low back pain (CLBP), resulting in reduced quality of life. Radiofrequency ablation (RFA) and corticosteroid injections are commonly utilized; however, direct comparative evidence specific to lumbar FJS remains limited. METHODS: A comprehensive search of PubMed, Embase, Web of Science, Cochrane Library, and Scopus (from inception to November 2025) was conducted to identify randomized controlled trials (RCTs) evaluating thermal RFA versus corticosteroid injections. The primary outcome measured was the Visual Analog Scale (VAS) at 3- and 6-months. Review Manager 5.4 was used to evaluate mean differences (MD) across outcomes using a random-effects model. RESULT: < 0.00001), favoring RFA. Heterogeneity was moderate to low across timepoints. Although significant, these results fell underneath the minimally important clinical difference (MCID). CONCLUSION: In our study, thermal RFA provided greater pain reduction than corticosteroid injections for FJS causing CLBP, suggesting a modest short-term advantage in pain reduction.
Authors
- Gilbert Siu (ORCID: https://orcid.org/0000-0002-4340-4414)
- Jason Tran (ORCID: https://orcid.org/0009-0007-4675-6320)
- Han Liu (ORCID: https://orcid.org/0000-0002-4899-9998)
- Justin Le
- Anish Rana
- Andrew Atschinow
- Lisa Huang
- Brandon Lazar
Institutions
- Health Net (US)
- Inspira Medical Center Vineland (US)
- Rowan University (US)
- University of Rochester (US)
Publication Details
- Journal
- Pain Management
- Published
- 2026-05-18
- DOI
- https://doi.org/10.1080/17581869.2026.2675483
- Primary Topic
- Spine and Intervertebral Disc Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00